Clinical Observation Of Xiaobanjiedu Decoction Combined With Pricking Blood Therapy In The Treatment Of Rosacea(Heat And Toxin Accumulate Skin Period)

Research purpose:To observe the clinical efficacy of xiaobanjiedu decoction combined with pricking blood therapy in the treatment of rosacea(heat and toxin accumulate skin period),and to explore its mechanism of action,in order to seek effective Chinese medicine therapy for the treatment of rosacea.Method: Sixty-four patients with rosacea were selected as the study subjects,used the method of randomized parallel control to divided the patients into treatment group and control group.The treatment group was treated with xiaobanjiedu decoction combined with pricking blood therapy,while the control group was treated with doxycycline hydrochloride combined with metronidazole gel.Four weeks for a course of treatment,and use two treatment,then recorded skin lesions and symptom scores,skin disease quality of life scores before treatment,4 weeks after treatment and 8 weeks after treatment in both groups.Evaluated the clinical effect of xiaobanjiedu decoction combined with pricking blood therapy on rosacea(heat and toxin accumulate skin period)by analyzing the scores of the two groups.Result: 1.Comparison of total effective rate: after the end of treatment,the total effective rate of the treatment group was 93.55%,and the total effective rate of the control group was 86.67%,There was a significant difference between the two groups(P<0.05),the treatment group was better than the control group.2.Intra-group comparison:Compared before treatment with the end of 4 weeks of treatment,and compared the end of 4 weeks of treatment with the end of 8 weeks of treatment,the scores declined.The symptoms of skin lesions and life quality scores of the two groups both decreased compared with before treatment.There was a significant difference in these comparison(P<0.05),indicating that both treatment regimens were effective.3.The scores of the two groups were compared before treatment,there was no significant difference(P>0.05),indicating that the two groups can be compared before treatment.Skin lesions,symptoms,and quality of life scores were compared between the two groups at the end of treatment 4 weeks,there was no significant difference between the two groups on the curative effect of the disease(P>0.05).Skin lesions,symptoms,and quality of life scores were compared between the two groups at the end of treatment 8 weeks,there was a significant difference between the two groups on the curative effect of the disease(P<0.05),this indicated that the therapeutic of the treatment group was better than the control group after the course of treatment.Conclusion: 1.The skin lesions,symptoms and quality of life scores of rosacea can be significant decreased by xiaobanjiedu decoction combined with acupuncture therapy.2.Xiaobanjiedu decoction combined with pricking blood therapy is a safe and effective treatment for rosacea.