Correlation Between TCM Syndromes And Coagulation Function In Unstable Angina Pectoris Of Coronary Heart Disease

Objective: To observe the correlation between clinical TCM syndromes and coagulation parameters(prothrombin time(PT),partial thromboplastin time(APTT),thrombin time(TT),fibrinogen(FIB))in patients with unstable angina pectoris(UA)with coronary heart disease.Provide a basis for clinical syndrome differentiation of unstable angina.Methods: 239 hospitalized patients with unstable angina pectoris according to the diagnostic criteria were collected and divided into 7 TCM syndromes according to clinical manifestations.Including: phlegm and blood stasis syndrome,qi and yin deficiency syndrome,qi deficiency and blood stasis syndrome,heart-blood stasis syndrome,liver and kidney yin deficiency syndrome,heart and spleen deficiency syndrome,qi stagnation and blood stasis syndrome.Among them,7 cases were not included in the observation statistics due to the small number of syndrome types,and the final number of observations was 232 cases.Record the patient's name,sex,age,course of disease and other general information,coagulation indicators,clinical data of complications(lacunar infarction),and analyze the correlation between TCM syndromes and clinical data.Excel 2018 and SPSS22.0 are applied to analyze and process the acquired data.ResultsAnalysis of 232 patients with unstable angina pectoris was as follows:1 Distribution of TCM syndromes : 88 cases(37.93%)of qi deficiency and blood stasis syndrome>65 cases(28.02%)with phlegm-blood stasis syndrome>58 cases(25%)of deficiency of both qi and Yin syndrome>21cases(9.05%)in the heart-blood stasis syndrome.2 Unstable angina pectoris with lacunar infarction,The syndrome type distribution was phlegm-blood stasis syndrome> qi deficiency and blood stasis syndrome > qi and yin deficiency syndrome> heart-blood stasis syndrome,phlegm-blood stasis syndrome and other three syndrome types were statistically significant(P<0.05).3 In the fibrinogen(FIB)index of coronary heart disease unstable angina pectoris,The heart-blood stasis syndrome was significantly statistically significant compared with the other three syndrome types(P<0.05).Among them,the heart-blood stasis syndrome > phlegm-blood stasis syndrome > qi deficiency and blood stasis syndrome,qi and yin deficiency syndrome.There were no significant differences between the TCM syndrome types of APTT,PT and TT(P>0.05),and there was no statistical significance.Conclusion1 Among the 232 cases of unstable angina pectoris of coronary heart disease,the syndrome of qi deficiency and blood stasis syndrome > phlegm and blood stasis syndrome > Qi and yin deficiency syndrome > heart-blood stasis syndrome.2 Among the 232 patients with unstable angina pectoris,the fibrinogen(FIB)value of heart-blood stasis syndrome was significantly higher than other syndrome types.