Clinical Observation On The Therapeutic Effect Of Diabetic Peripheral Neuropathy By "Purge Stomach And Tonify Spleen" Acupuncture Therapy Associate With Filiform Fire Needle

Objective To compare the differences of clinical therapeutic effect between "Purge Stomach and Tonify Spleen" acupuncture therapy associate with fire filiform needle and conventional acupuncture method for diabetic peripheral neuropathy(DPN).Methods A total of 60 patients compliant with standard were randomly divided into two groups,both are treatment group and control group with the contain of 30 cases in each group.Both groups were implemented with fundamental treatment of blood glucose regulation,and remain consistency of patient's origin medication simultaneously.The intervention of "Purge Stomach and Tonify Spleen" acupuncture therapy associate with filiform fire needle and conventional acupuncture method were applied into treatment group and control group respectively.The major acupoints of treatement group are Zhongwan(RN 12),Zusanli(ST 36),Neiting(ST 44),Pishu(BL 20),Sanyinjiao(SP 6),and Taibai(S P3)bilaterally.The method of reducing by lifting,thrusting,twirling,and rotating manipulation were applied to Zhongwan(RN 12),Zusanli(ST 36),Neiting(ST 44).Conversely,the method of reinforcing by lifting,thrusting,twirling,and rotating manipulation were applied to Pishu(BL 20),Sanyinjiao(SP 6),and Taibai(SP 3).The needles were kept for 30 minutes,except Pishu(BL 20).The fire filiform needle was performed after the treatment above,with the major acupoints of Hegu(LI 4),Quchi(LI 11),Yangxi(LI 5),Waiguan(SJ 5),Zusanli(ST 36),Yanglingquan(GB 34),Jiexi(ST 41),Kunlun(BL 60),Taichong(LR 3),and Ashi point.The inferior 1/3 part body of needles were burned in flame until the appearance of redness,and pierce the needle quickly into the acupoints.The method above was repeated about 3 to 5 times,then the needle was left in the acupoint for the last time.The major acupoints of control group are bilateral Yishu(EX-B3),Pishu(BL 20),Weishu(BL 21),Shenshu(BL 23),Sanyinjiao(SP 6),Neiting(ST 44),Zusanli(ST 36).The additional points Quchi(LI 11),Hegu(LI 4),Yangxi(LI 5),Waiguan(SJ 5),Wangu(SI 4)were added for upper limb lesion;Yanglingquan(GB 34),Shenmai(BL 62),Zhaohai(KI 6),Kunlun(BL 60),Qiuxu(GB 40),Jiexi(ST 41)were added for lower limb lesion.The method of even reinforcing-reducing was manipulated in this group,and the needles were kept for 30mintes.Both groups were given in total of 3 treatment courses,and 1 month considered as 1 treatment course,3 times per week with 1 day interval.The TCM symptom score,Toronto clinical scoring system(TCSS),nerve conduction velocity(NCV)and blood glucose parameters(such as,FPG,2hPG and HbAlc)were compared between both groups,and the treatment efficacies were evaluated.Result1.TCM symptom score:The TCM symptom score of both groups were reduced significantly after the treatment(both P<0.05).As compared with the control group,the TCM symptom score of the treatment group was lower than the control group,and the difference was statistically significant(P<0.05).2.Toronto clinical scoring system(TCSS):The TCSS score of both groups were reduced significantly after the treatment(both P<0.05).As compared with the control group,the TCSS score of the treatment group was lower than the control group,while the differences between both treatment group and control group were statistically significant(P<0.05).3.Nerve conduction velocity:After the intervention for both groups,the nerve conduction velocity of Common Peroneal nerve's motor nerve conduction velocity(MCV)and Gastrocnemius nerve's the sensory nerve conduction velocity(SCV)were both higher than before intervention,the difference was statistically significant(P<0.05).In term of the increasing degree on nerve conduction velocity,the treatment group has a distinct improve in Common Peroneal nerve's MCV and Gastrocnemius nerve's SCV compared to the control group,while the differences in between both groups were statistically significant(P<0.05).However,the changes of Median nerve's MCV and SCV after intervention for both groups,the differences of comparison was not statistically significant(P>0.05).4.FPG,2hPG,HbAlc:After the intervention,both groups resulting a distinct reduced on blood glucose parameters FPG,2hPG and HbAlc,and it shown with statistically significant in term of the differences between before and after intervention for both groups(P<0.05).However,the treatment group has a better improvement degree than the control group,and the differences was statistically significant(P<0.05).Conclusion Both the treatment group and control group could result in improve of patient's symptoms,decrease in TCSS score,elevate the nerve conduction velocity and maintain a better blood glucose level.In addition,the treatment group has an advantage in term of overall efficacy.