Risk Factors Of Gastroesophageal Reflux Disease And TCM Constitution Identification

Objective:To conduct a case-control study of patients with gastroesophageal reflux disease and non-gastroesophageal reflux disease,to summarize the characteristics of life,diet,and physical fitness,to explore the risk factors and physical characteristics that affect the incidence of gastroesophageal reflux disease,and to improve gastroesophageal reflux disease The traditional Chinese medicine prevention and cure path of the disease can provide ideas for the treatment and prevention of the disease.Methods:Patients with gastroesophageal reflux disease(100 cases)who were diagnosed in the Department of Gastroenterology and Physical Examination Center of Nanjing Integrated Chinese and Western Medicine Hospital from January 2019 to January 2020 were selected as the case group,and went to the hospital for digestion at the same time Kefei GERD patients and healthy people in the physical examination center served as control group(400 cases)in a case-control study.Samples were collected from the case group and the control group at a ratio of 1:4,and gender,ethnicity,age(±5 years),and onset time(within 30 days difference)were used as matching conditions.The subjects were studied through questionnaires,which included a gastroesophageal reflux disease questionnaire(Gerd Q scale)and possible factors related to the incidence of gastroesophageal reflux disease(general conditions,physical characteristics,lifestyle,dietary habits,Psychological and emotional factors),physical characteristics of traditional Chinese medicine.A database was established using Microsoft Excel,and all data was analyzed statistically using SPSS23.0 software.Based on the theory of traditional Chinese medicine combined with literature research,a comprehensive statistical method was used to draw conclusions.Results:A total of 100 cases were included in this study and 400 were in the control group.302 men and 198 women participated in the survey.The average age in the case group was 44.070±1.354 years,and the average age in the control group was 32.123±0.586 years.Median BMI in the case group:23.438,Median BMI in the control group:21.815,A high BMI(P=0.000)was an influential factor for the onset of GERD.Among lifestyle habits and diet preferences,smoking(P=0.036),drinking(P=0.046),anxiety and depression(P=0.029),coffee(P=0.037),carbonated beverages(P=0.005),and snacking preferences(P=0.01),not eating breakfast(P=0.029),eating too fast(P=0.029),eating too full(P=0.029),eating too hot(P=0.029),lying supine immediately after a meal(P=0.029)two There was a statistical difference between the groups.By logistic regression analysis:age(Z=3.524,P=0.000),OR(1.153);high-fat food(Z=2.087,P=0.037),OR(1.484).Age and high-fat diet are risk factors affecting GERD,which are positively correlated with the incidence of GERD.Constitution:By logistic regression analysis:Qi deficiency(P=0.038),OR(4.333);Yang deficiency(P=0.021),OR(4.829).The deficiency of yang and the deficiency of qi are biased constitutions that may affect the onset of GERD and have a positive correlation with the incidence of GERD.Conclusion:This study showed that the factors associated with.the onset of gastroesophageal reflux disease are:high BMI,smoking,drinking,sleep disorders,coffee,carbonated drinks,snacks,anxiety,skipping breakfast,eating too fast,eating too much,eating too hot Supine immediately after a meal;risk factors for gastroesophageal reflux disease are age,high-fat diet.The constitutions that are likely to cause gastroesophageal reflux disease are yang deficiency and qi deficiency.The occurrence,development,and recurrence of gastroesophageal reflux disease are closely related to patients' usual dietary intake.Reasonable diet structure,reducing or avoiding risk factors,and improving lifestyle can reduce the incidence of gastroesophageal reflux disease.In addition to avoiding the dangers caused by bad living habits and eating habits,you should also adjust your bias constitution to avoid taking drugs and foods that aggravate your constitution.The risk factors and physical identification in this study laid the foundation for the establishment of the GERD evaluation system,provided statistical support for the controversial risk factors and biased physique,and also strengthened the convincing evidence in similar studies.The risk factors and physical characteristics of the disease population provide new theoretical ideas for the prevention and treatment of gastroesophageal reflux disease.