Clinical Observation Of Huazhuodingxuan Decoction On Posterior Circulation Ischemic Vertigo With Mucous DePosition

ObjectiveBy means of modern medical research,through observation and comParison of the relevant examination indexes before and after the treatment of Posterior circulation ischemic vertigo(Phlegm and blood stasis)by huazhuodingxuan decoction,theoretical basis and clinical exPerience were Provided for the treatment of Posterior circulation ischemic vertigo with Phlegm and blood stasis.MethodsSelected meet sPutum silt junction after each cycle is 72 vertigo Patients,random number,according to random number table is divided into two grouPs,each grouP of 36 PeoPle,two grouPs of foundation treatment to give Shu Xie Tong injection 2 ml x 3,day at a time,the intravenous driP,control grouP Pure foundation treatment,the treatment grouP use turbidity anti-dazzle souP with Shu Xie Tong injection combined treatment of traditional Chinese medicine(TCM)for each 200 ml,in the morning and once;Two grouPs of Patients treatment cycle for 14 days,in strict accordance with the in Put criteria and excluding standard,eventually the number of treatment grouP was 31 PeoPle,the number of control grouP 30,by observing two grouPs of Patients before and after treatment of vertigo severity,TCM sym Ptom score,hcy,blood li Pids,blood viscosity,su Peroxide dismutase(sod),TCD and other indicators,ultimately through s Pss17.0 software for statistical analysis.ResultComParison of efficacy: after rank-sum test,P < 0.05,the difference was statistically significant.Among the Patients in the treatment grouP,5 cases were cured clinically,accounting for 16.13% of the total cases,and 15 cases were significantly effective,the Pro Portion was: 43.39%,8 Patients with effective,accounting for 25.81% of the total,3cases ineffective,accounted for 9.68%,total effective rate 90.32%,control grouP Patients,clinical recovery(3 cases),accounting for 10% of the total,5 cases had marked effect,occu Pying 16.67%,14 cases effective,accounted for 46.67%,8 Patients with invalid,accounted for 26.67%,total effective rate 73.3%,tiP can effectively im Prove the sym Ptoms in both grouPs,but change chaotic set anti-dazzle souP treatment grouP and the control grouP significantly.This indicates that huazhuodingxuan decoction has significant clinical efficacy in the treatment of Postcirculation ischemic vertigo with mucous de Position.ComParison of vertigo severity score and TCM syndrome score before and after treatment between the two grouPs:There was no significant difference between the two grouPs(P > 0.05)in vertigo severity and TCM sym Ptom score before treatment.The vertigo severity score and TCM sym Ptom score of the two grouPs were com Pared before and after treatment,and the difference was statistically significant(P < 0.05),indicating that both grouPs were effective in treatment.After treatment,the difference between the two grouPs was statistically significant(P < 0.05),and the treatment grouP was su Perior to the control grouP,indicating that huazhuodingxuan decoction could significantly im Prove the severity of vertigo in Patients with mild vertigo and im Prove the TCM syndrome score.Transcranial do PPler analysis: before treatment,the average blood flow velocity of LVA,RVA and BA in the two grouPs was com Pared,P>0.05,no significant difference,with com Parability.After treatment,the average blood flow velocity of BA and LVA in the two grouPs was increased com Pared with that before treatment in the same grouP,and the increase of the average blood flow velocity in the treatment grouP was more significant than that in the control grouP(P<0.05).After treatment,P > 0.05 was found in the comParison of RVA between the two grouPs after treatment and before treatment,and the difference was not statistically significant.After treatment,the blood flow velocity of both LVA and BA increased,indicating that the decoction can effectively im Prove the blood flow velocity of the left vertebral artery and basilar artery.ComParison of blood li Pid status: TC and TG before treatment were com Pared between the two grouPs,P > 0.05,which was com Parable;TC and TG after treatment were com Pared between the two grouPs,P < 0.05,which was statistically significant;TC and TG of the Patients after treatment were decreased com Pared with before treatment,which was statistically significant.After treatment,t test was Performed in the treatment grouP and the control grouP,P<0.05.TC and TG in the two grouPs were com Pared,and there was a difference between the two grouPs.In addition,the effect of the treatment grouP was more significant in im Proving Patients' blood liPid and reducing TC and TG.ComParison of homocysteine: before treatment,Hcy of the two grouPs showed no significant difference after t test,P>0.05,which was com Parable.After treatment,Hcy in the two grouPs was lower than that in the same grouP before treatment,with statistical significance(P<0.05).There was also a significant difference in Hcy between the two grouPs after treatment(P<005),which suggested that the effect of the treatment grouP was more significant than that of the control grouP in reducing Hcy.This indicates that huazhuodingxuan decoction can effectively reduce the risk factors of cerebrovascular diseases and thus achieve the PurPose of Preventing Posterior circulation ischemia.ComParison of Plasma viscosity indexes before and after treatment between the two grouPs: before treatment,there was no significant difference in Plasma viscosity between the two grouPs(P>0.05),which was com Parable.After treatment,the Plasma viscosity of the two grouPs was lower than that of the same grouP before treatment(P<0.05).There was also a significant difference in Plasma viscosity between the treatment grouP and the control grouP after treatment(P<005),suggesting that the effect of the treatment grouP was more significant than that of the control grouP in reducing Plasma viscosity.This indicates that huazhuodingxuan decoction can effectively reduce Plasma viscosity and im Prove blood circulation.Two grouPs before and after treatment the comParison of su Peroxide dismutase(SOD): before the treatment,com Pared two grouPs of Patients with SOD,P > 0.05,com Parable,"change chaotic dizzy sou P" grouP of SOD comParison before and after the treatment,while a SOD was increased after the treatment,but comParison before and after the treatment(P > 0.05,no statistically significant difference,SOD comParison before and after the treatment of the control grouP(P > 0.05),and no statistically significant difference,instructions for two grouPs of drug effects on SOD index is not clear.ConclusionBased on the basic treatment of shuxuetong injection,huazhuidingxuan decoction has a definite theraPeutic effect in the treatment of Posterior circulation ischemic vertigo with mucous dePosition,which can significantly reduce the severity score of vertigo symPtoms and TCM syndrome score,regulate the level of blood liPid and blood viscosity,accelerate the blood flow velocity of vertebrobasilia artery,and reduce the HCY index.The influence on SOD index is not clear.