Effects Of 4 Week Aerobic Training And Dietary Intervention On Serum HSP70 And SIRT1 Levels In Obese Male Adolescents

Objective:in recent years the adolescent obesity has become a common Phenomenon,this article through to ParticiPate in wuhan sPorts college hao qian summer camP of obese male adolescents through four weeks aerobic training and diet intervention in body comPosition and blood heat shock Protein 70(HsP70),silent information adjustment factor 1(Sirt1)level changes,discusses the subjects 4 weeks after the intervention to imProve the effect of body comPosition and inflammatory reaction Process,for scientific exercise to lose weight and obesity in Patients with clinical diagnosis and treatment Provide a reference basis.Methods:the subjects for 10 hao qian summer camP in wuhan institute of Physical education of the obese male adolescents 12~18 yearsold,the aerobic training and diet control means four comPrehensive closed intervention,medium intensity aerobic exercise for a long time,as the Primary way of sPorts training,strength training as suPPlementary training.The forms of sPorts include fast walking,jogging,swimming,recreational ball games,aerobic exercises and sPorts games.Every morning do about 40 minutes of exercise,on,and in the afternoon for about 2 hours of exercise,each exercise PreParation and organizing activities for 10 minutes or so,2~3 times during the exercise short rest,after dinner for half an hour walk;Train every day.Exercise intensity is 60~70%maximum heart rate(120~140beats/min).During the exercise,the coach will arrange short rest time according to the condition of the subjects.Diet according to the individual basal metabolic rate arrangement resPective corresPonding configuration,the ProPortion of sugar,fat,Protein is resPectively55~65%,20~35%,10~15%,three times a day caloric allocation ProPortion is about3:4:3.Body comPosition and serum HsP70 and Sirt1 levels were detected before and after 4weeks of intervention.Results:(1)after 4 weeks aerobic training combined with dietary interventions,obese male adolescents body comPosition(body weight,body fat Percentage,fat mass,body mass index,fat soft body weight,fat weight,about arms and body fat mass,and uPPer or lower limbs fat soft body weight),etc.Each index declined obviously,show very significantdifference(P<0.01).(2)after 4 weeks of aerobic training combined with diet intervention,the serum HsP70(heat shock Protein 70)level decreased significantly(P<0.01),and the serum Sirt1(silent information regulator1)level increased significantly comPared with that before weight loss(P<0.01).Concision:(1)4 weeks of aerob training combned wm detary intervention can imProve the body comPosion of obese male adolescents to achieve short-term weight ass.(2)4 weeks of aerobic training combined with dietary intervention can uP-regulate serum Sirt1 level,down-regulate serum HsP70 level,and imProve the chronic inflammatory resPonse state of obese male adolescents.