Relevant Research On The Intervention Of Traditional Chinese Medicine In Insulin Resistance Of Type 2 Diabetes Based On Data Mining

Purpose : To explore the prescription regularity of Chinese medicine for insulin resistance of type 2 diabetes and the treatment to provide reference for clinical treatment.Material and method:Using the classification method,Retrieving clinical literature on insulin resistance in type 2 diabetes mellitus using the treatment of TCM or combine traditional Chinese and western medicine from January 2013 to January 2018 in the Chongqing China How Net VIP database.to regulate the selected terms in the literature of prescription drugs,and extract the noun,title,publication time,prescription,medicine and other related information,frequency analysis and cluster analysis used Excle software and SPSS24.0 software,visual display used Gephi software.Results:Selected required articles 1190,included in the insulin resistance of type 2 diabetes clinical research 143,collected 147 prescriptions,the overall situation of drug treatment of insulin resistance in type 2 diabetes mellitus can be seen that using more Astragalus,Poria,radix salviae miltiorrhizae,Rhizoma Coptidis,radix rehmanniae,the application frequency is above 40%.Astragalus,tuckahoe,Salvia miltiorrhiza,Rhizoma Coptidis,raw land,Ge Gen,yam,Ophiopogon,licorice,and Atractylodes are the first ten traditional Chinese medicinal materials used.According to the efficacy of the materials,all drugs were classified,and the most used drugs were deficiency-nourishing drugs,followed by the drugs of clearing heat and activating blood and removing blood stasis.Among the deficiency-nourishing drugs,the main medicine is supplementing qi and supplementing Yin,which is 58% and 25% respectively,and only 5% and 12% are tonifying yang and enriching blood.The results of cluster analysis is eight groups,the drug combinations are:(1)kuhseng,Digupi,Polygonum multiflorum,epimedium,litchi,Atractylodes,Perrin,ginseng,Poria,Cornus officinalis.It is mainly to invigorate the kidney and the spleen and dispel wet.(2)Salvia miltiorrhiza,Ge Gen,yellowish essence,Anemarrhena and Rhizoma Coptidis.It is mainly nourishing yin and clearing heat and activating blood.(3)peony skin,cooked land,yam and Alisma orientalis.To Nourish Qi and yin and to clear heat.(4)tangerine,hawthorn,Pinellia ternata,Atractylodes,licorice,Codonopsis and coix seed.Invigorating Qi,invigorating spleen and resolving phlegm.(5)Radix Scutellariae and rhubarb.It is dominated by clearing away heat and activating blood.(6)angelica,Paeonia lactiflora,bupleurum,ghosts and arrow feathers.To regulate Qi and active blood mainly.(7)Ligusticum chuanxiong,radix paeoniae rubra,mulberry leaf and leech.It is dominated by activating blood and clearing heat.(8)the fruit of Chinese wolfberry,Radix trichosanthis,Radix Astragali,rehmanniae,ophiopogon root,Schisandra chinensis,Radix scrophulariae.To Nourish Qi and nourish Yin mainly.Conclusion:T2DM insulin resistance is based on deficiency of Qi and Yin,and dryness heat is the criterion.Phlegm dampness accumulation,body deficiency and blood stasis are closely related to the occurrence of T2 DM insulin resistance.Qi supplementing should be the main point of treatment.Nourishing Yin,clearing away heat and activating blood circulation is an effective way to treat it.