| The objectives of this research were; (1) to provide a thorough review of existing scaffolding systems, and (2) to explore the electrospinning process as a means for developing a three-dimensional scaffold from a polymer/ceramic blend.; The review of existing scaffolding systems provided a thorough reference source with information on the material(s), fabrication method, and the physical and structural characteristics. SEM images were also produced for visual representation and for microstructure examination.; Analysis of the electrospinning process provided the optimum parameters for spinning polycaprolactone in acetone, which were; tip to target distance—6 inches, voltage—15 kV, concentration—12%, and flow rate—0.3 ml/min. The ability to electrospin a polycaprolactone/hydroxyapatite blend was demonstrated, although modifications must be implemented to optimize the spinning of the blend. Finally, several attempts were tried to increase the thickness of the electrospun scaffolding including; targets with different conductivities, using a water spray coating to improve the conductivity through the fibers, target modification, and coating the fibers with carbon to remove the electrical charge. No structures beyond 0.2–0.3 mm have been reported. All efforts to obtain a thicker fiber mat were ineffective with the carbon coating and the target modification showing the most potential for success. Future research should continue to build on the results of this study. |
