New Antifungal Polyester Based On Menthol

As one of the most used materials in the world,polyester is widely applied in medical devices,food packaging,textile materials and other industries.However,it is well known that polyester has non-antibacterial properties,which causes the productions of polyester often provide a "hotbed" for microbial(bacteria or fungi)growth and adhesion.A series of problems,such as medical infection and food safety is easy to be caused by microbial contamination of the productions of polyester.Inspired by the strategy of stereochemical antibacterial modification,our subject has modified the structure of polyethylene terephthalate(PET),which is currently the most widely used,by directly polymerizing with terephthalic acid(TA)to convert menthol The triazine monomer is inserted into the main chain of PET to prepare a new menthol-containing triazine polyester(PMTA)whose structure is similar to PET.Taking PET as a control,the broad-spectrum microbial anti-adhesion properties of PMTA were studied.And designed further experiments to confirm the effect of polyester flexible chain on the performance of stereochemical anti-adhesion.The main research conclusions are listed in below:1.Two new monomer compounds MT and MET were synthesized and characterized by 1H NMR,13C NMR,FT-IR,UV,MS,EA.2.A new menthol-based antibacterial polyester PMTA and its control PMSA were synthesized and characterized by 1H NMR and FT-IR.3.PMTA polyester material has broad-spectrum anti-bacterial properties,and has a strong inhibitory effect on Escherichia coli and Staphylococcus aureus.4.PMTA polyester material has excellent antifungal properties,good antiadhesion effect on Aspergillus niger,and the antifungal effect is long-lasting.5.Through comparing the antibacterial effect and water contact angle with PMSA and the observation of the zone of inhibition,it is proved that the antibacterial mechanism of PMTA is the surface stereochemical structure of menthol.6.PMTA has good stability and biocompatibility.As an antibacterial polyester,it has great development potential for environmental protection,medicine,food and other fields.