In recent years,the increasing trend of diabetes prevalence has not been effectively controlled.Many patients have diabetic with serious complications.Therefore,doctors need to make a series of reasonable treatment plans,according to the changes of physiological parameters of patients after taking medicine.Now,doctors’ methods of obtaining patients’ physiological information mainly rely on independent electrophysiological instruments.But this method has many disadvantages: long measurement period,traumatic detection,etc.In this situation,this paper,based on Linux embedded technology and medical electronic technology,discusses the design of a non-invasive living physiological and biochemical detector.The detector can measure and display a variety of important physiological and biochemical parameters of the human body,including blood oxygen saturation,hemoglobin concentration,pulse wave,systolic blood pressure,diastolic blood pressure,heart rate and blood glucose value,etc.At the same time,it can also store and read physiological parameters for a long time.This paper mainly does the following research:(1)Principles: Based on the research experience provided by a large number of literatures,the theoretical basis of this study includes photoplethysmography(PPG),Lambert-Beer law,pulse wave transit time measurement and energy metabolic conversation law.(2)Hardware design: A single non-invasive detection probe was designed to collect and measure multiple physiological parameters and reduce the impact of multiple sensors and invasive detection on patients.In addition,ARM(S5PV210)was used as the core of the system.And driving module,communication module and power module were designed and researched.Finally,the PCB was drawn and the test prototype was made based on the previous research.(3)Software design: Physiological parameter measurement programs and data processing algorithms were designed and written in The Linux operating system.The serial port screen,for the convenient operation and human-machine interaction,was used as monitor to build the human-computer interaction interface with USART HMI.(4)Experimental: The experimental prototype was used to measure the physiological parameters of 22 volunteers.And parameters were compared with those of standard instruments.It is not hard to find that the non-invasive living physiological and biochemical detector designed in this paper has a high correlation with the comparison instruments.Meanwhile,the detector has good operability,accuracy,stability and repeatability.In summary,the non-invasive living physiological and biochemical detector designed in this study has effectively detected various physiological parameters of the human body.This study can provide more reference values for the study of pharmacodynamics of diabetes. |