The Investigation And Establishment Of Technology Regulations For Prevention And Therapy Of Trace Element Metabolism Diseases In Stall-feeding Mutton Sheep In Xinjiang

In order to understand the incidence and harmfulness of trace element metabolism diseases in main stall-feeding mutton sheep areas in Xinjiang,provideing theoretical basis for scientific prevention and therapy of trace element metabolic diseases in mutton sheep,and establish their therapy local standards.The feeding and management status,dietary composition and common clinical symptoms of mutton sheep in some farms and enterprises were investigated and counted in Xinjiang from 2015 to 2017 in this study,and the contents of trace elements in main forage materials(such as corn,bran,alfalfa,reed,soybean,oil residue)and supplementary feeding products(licking bricks)were determined.The following results have been obtained after statistical analysis1.The clinical problems(abnormal performance of mutton sheep)threatening the development of mutton sheep industry Xinjiang include:allotriophagy(gnawing on walls or/and gnawing on soil)(mineral nutrition metabolic diseases,accounting for 56.2%of the total number of sheep farms/herds surveyed(the same as below));sudden death of lamb(micronutrient metabolic diseases and infectious diseases,accounting for 53.4%);postpartum paralysis of ewes(mineral elements metabolic diseases,accounting for 40.6%);eating hair symptoms each other(mineral elements metabolic disease,accounting for 40.2%);hindlimb paralysis of lamb(mineral elements metabolic disease,accounting for 34.9%);prenatal paralysis of ewes(nutrition metabolic disease,accounting for 34.1%).2.The data of trace element content in main feed materials of Xinjiang mutton sheep and in supplementary products(licking bricks)for Xinjiang mutton sheep were obtained,which laid a solid foundation for further research and development of prevention and control products for trace element deficiency of mutton sheep in Xinjiang.After further analysis of the results,the following conclusions are drawn:1.Almost every trace element nutrition metabolism disease will have specific regular changes in blood routine and serum biochemical indicators before(recessive)symptoms or after(dominant)symptoms.This change has good repeatability and sensitivity,and can be used as an important clinical diagnostic reference index.It is of great significance to guiding the formulation of technical regulations for the prevention and treatment of trace element metabolic diseases。2.The data of trace element content in forage(atomic absorption spectrometry)showed that there was strong correlation between trace element deficiency and main forage types,but weak correlation with trace element content in soil.The regional correlation of micronutrient metabolic diseases in mutton sheep was also due to the difference of main type of forage materials in different regions。3.The major trace element metabolic diseases which were harmful and should be paid attention to in Xinjiang were:lamb white muscle disease(selenium deficiency),anemia(iron,copper and/or cobalt deficiency)and white liver disease(cobalt deficiency),lamb waist swing disease(copper deficiency),lamb growth retardation(zinc deficiency),and osteoporosis(manganese deficiency).In the end,as the carrier of the research achievement,three local standards for control trace element metabolic diseases were compiled and published:(1)《The Technical Regulation for Controlling White Muscle Disease in lambs》(DB 65/T 3967-2016);(2)《The Technical Regulation for Prevention and Cure of Copper Deficiency Disease of lambs》(DB 65/T 4112-2018);(3)《The Technical Regulation for Prevention and Treatment of Cobalt and Vitamin B12 Deficiency in sheep》(DB 65/T 4111-2018).It is hoped that the research results can be rapidly applied to the production practice of mutton sheep farming in our region.