Clinical Observation On Maxing Shigan Decoction Combined With Yinqiao Powder Combined With Blood-activating And Blood Stasis-removing Drugs In The Treatment Of Pediatric Pneumonia

Objective :To observe the clinical efficacy of Maxing Shigan Decoction and Yinqiao San combined with Salvia miltiorrhiza and peach kernel medicine in the treatment of infantile pneumonia(diagnosis of traditional Chinese medicine:pneumonia,wind-heat closed lung syndrome),and make a comprehensive evaluation of its treatment of infantile pneumonia.To explore its mechanism of action,to provide clinical basis for the popularization,application and research of this prescription in the treatment of pneumonia,asthma,wind-heat closed lung syndrome,and to provide ideas for the development of in-hospital preparations.Methods :A total of 67 children with pneumonia(diagnosis of traditional Chinese medicine: pneumonia asthma,wind-heat closed lung syndrome)in Yantai Hospital of Traditional Chinese Medicine were selected and randomly divided into the experimental group and the control group.Both groups were given oral Chinese medicine decoction(Maxing Shigan Decoction and Yinqiao Powder).Addition and subtraction),and symptomatic treatment such as anti-infection,antipyretic,and rehydration were given according to the changes of the children’s condition.The experimental group was added with Danshen-Peach Kernel medicine pair on the basis of the traditional Chinese medicine prescription used in the control group.The clinical efficacy of the two groups of children was observed before treatment,after 3 days of treatment,and after7 days of treatment(refer to the main indicators,secondary indicators,blood test indicators,efficacy evaluation indicators,etc.),and statistical methods were used to sort out and analyze,and draw conclusions.Results :1.The clinical data were statistically processed,and there was no significant difference between the experimental group and the control group in gender,age,onset time,proportion of mycoplasma infection,and lesion location(p>0.05).There was no significant difference between the experimental group and the control group in the evaluation of admission conditions(p>0.05).2.After 3 days of treatment,the scores of fever,cough and sputum in the two groups were significantly different from those before and after treatment(p<0.01),indicating that the two groups of medicines can improve the symptoms of fever,cough and sputum in children.Through the comparison between groups,it can be seen that the experimental group and the control group have differences in the improvement of fever and cough(p < 0.05),and there is no difference in the improvement of sputum indicators(p > 0.05);There were differences between the two groups in the improvement of some secondary symptoms(appetite,stool,heat syndrome,tongue image)(p < 0.05):There were differences in the indicators of complexion,sweating,stool and tongue in the test group(p < 0.01),and there were differences in the indicators of complexion and sweating in the control group(p < 0.05),which indicated that in terms of alleviating secondary symptoms,the overall experimental group was significantly better.The effect is better than that of the control group,The control group can improve the complexion and abnormal sweating of the children,and the experimental group can also improve the abnormal stool and tongue image of the children on this basis.After 7days of treatment,the overall efficacy of the two groups was statistically significant(p < 0.05),the experimental group was 93.75%,the control group was 87.50%,the experimental group was better than the control group.There were differences in the total score,the sum of the main syndrome score and the secondary syndrome score(p<0.01),and the experimental group was better than the control group;some single index scores(fever,cough,expectoration and appetite,etc.)were significantly different(p < 0.05),and the experimental group was better than the control group;Other indicators(asthma,lung auscultation,face color,stool,fever,heart rate,sweating,tongue,etc.),no significant difference between the two groups(p > 0.05).3.In laboratory examination,there was no significant difference in the number of WBC,N%,L%,CRP,PCT,D-dimer between the two groups before treatment(p>0.05).After 7 days of treatment,there was no significant difference in WBC number,N %,L % between the two groups(p > 0.05),and there was significant difference in CRP,PCT and D-dimer(p < 0.01).It shows that the experimental group has advantages over the control group in improving CRP,PCT,D-dimer and other indicators,but it is not enough to explain that the combination of Maxing Shigan Decoction and Yinqiao Powder with Danshen-Peach Kernel Medicine is effective in children with pneumonia and asthma(wind-heat closed lung syndrome).improvement in the number of WBC during treatment.Conclusion:1.After the combination of Danshen-Peach Kernel medicine pair,the efficacy of the prescription in treating pneumonia and asthma(wind-heat closed lung syndrome)is higher than before,and it has obvious advantages in improving symptoms(primary syndrome and secondary syndrome),and the program is safe.No adverse events occurred during the process.2.The combination of Maxing Shigan Decoction and Yinqiao Powder with Danshen-Peach Kernel Medicine has an ideal overall effect on the treatment of infantile pneumonia(diagnosis of traditional Chinese medicine: pneumonia asthma and wind-heat closed lung syndrome),which provides ideas and methods for clinical application and in-hospital preparations.