| Objective: In this study,we took the oral soup "Warm Kidney and Blood Stasis Drink" against the oral "Ding kun Dan" for the treatment of late menstruation(blood stasis and renal deficiency proof),and studied the data to see how these patients’ clinical symptoms and menstrual cycle improved.Methods:Patients who visited the clinic from December 2021 to December 2022 and met the diagnostic criteria were selected as the enrolled cases and divided into 36 cases each in the treatment and control groups.During the treatment,patients in the treatment group were allowed to take warm kidney and blood stasis drink orally,while patients in the control group were instructed to take Ding kun Dan orally.At the end of 3 menstrual cycles of treatment,the improvement of menstrual conditions and concomitant symptoms were observed in both groups of patients after treatment.The clinical trial data of the patients were analyzed at the end of the study to calculate the efficiency of the two treatment groups and to analyze the mechanism of action.Results: 1.Complete analysis: The therapy group comprised of 34 patients,and the quick guide rate was 91.18%.Among these,8 cases(or 23.53% of them)were cured,13cases(or 38.24% of them)were effective,10 cases(or 29.41% of them)were effective,Three patients(8.82%)whose menstrual status and symptoms did not improve significantly after treatment,i.e.,were ineffective.The total effective rate of the control group was at81.25%,with 3 cases being cured(or 9.38% of them),6 being effective(or 18.75% of them),17 being successful(or 53.13% of them),and 6 being ineffective(or 18.75% of them).When compared between the two groups,the treatment group’s effect was clearly discernible.2.The comparison of total scores before and after treatment: the comparison of total scores before and after treatment between the self-prepared Kidney and Blood Stasis Drink group and the Ding kun Dan group showed that P=0.000<0.05 for each group,indicating that both the self-prepared Kidney and Blood Stasis Drink group and the Ding kun Dan group could improve the total scores;the test between the two groups showed that P=0.001<0.05,indicating that the self-prepared Kidney and Blood Stasis Drink group was more effective than the Ding kun Dan group.The effect was significant.3.Comparison of the main symptoms before and after treatment: The analysis of the main symptoms before and after treatment between the two groups showed that: P=0.000<0.05 for intra-group comparison,P=0.016 for late menstruation,P=0.043 for menstrual volume,and P=0.032 for menstrual texture,all P<0.05.This indicates that both treatment methods can shorten the patient’s cycle and improve the menstrual volume and texture,but the comparison of the self-prepared warm kidney and blood stasis drink is more effective than that of The efficacy of Ding kun Dan was more significant.4.Comparison of secondary symptoms before and after treatment: The analysis of the secondary symptoms scores before and after treatment between the two groups revealed that: P=0.000<0.05 for intra-group comparison,P=0.083>0.05 for waist and knee weakness,P=0.479>0.05 for dizziness and tinnitus,P=0.025<0.05 for dull complexion,and P=0.005<0.05 for menstrual abdominal pain.improve the patients’ lumbar and knee weakness,dizziness and tinnitus,dull face,and menstrual abdominal pain.In terms of waist and knee weakness,dizziness and tinnitus,the two groups did not improve significantly,while in terms of facial dullness and menstrual abdominal pain,the efficacy of self-prepared warm kidney and blood stasis drink was more significant than that of Ding kun Dan.5.Follow-up of patients with normalized menstrual cycle after treatment:The patients’ cycles were followed up by telephone or We-Chat in 3 month after the treatment course,and the maintenance rate of normalized menstrual cycle was 86.36% in the patients who returned to normal after treatment,compared with 66.67% in the control group,which proved the long-term efficacy of the self-prepared Warm Kidney and Stasis Drink.Conclusion: After a pilot study,we found that the treatment of late menstruation(evidence of kidney deficiency and blood stasis)with self-prepared Warm Kidney and Blood Stasis Drink is more effective.This formula can significantly improve the menstrual cycle,menstrual volume,menstrual color and texture and their accompanying symptoms,and it has good efficacy in maintaining normal menstrual cycle in the distant period.No clinical adverse conditions have been found worthy of promotion. |