Study On The Distribution Of Six Meridian Syndromes And Related Factors Of Diabetic Diarrhea Based On Treatise On Febrile Disease

Purpose:To explore the distribution law of six meridian syndrome differentiation in patients with DD,and further study the relationship between six meridian syndrome differentiation and gender,age,duration of DM,BMI,Hb A_1Cand fasting C-peptide,so as to provide objective theoretical basis for clinical diagnosis and treatment of the disease,and develop new ideas of TCM syndrome differentiation in DD.Material and method:This study strictly referred to the diagnostic criteria of DM and DD,as well as the inclusion and exclusion criteria,and collected 101 patients with DD who visited the Endocrine Rehabilitation Department of the Affiliated Hospital of Liaoning University of Traditional Chinese Medicine from September 2021 to December 2022,and collected the general data,clinical symptoms data,laboratory test data and other relevant information of the patients.Fill in the collected data in the DD Six Meridians Syndrome Differentiation Questionnaire（see Attached Table 1）,combine with the guidance of the instructor,classify the patients according to the proposed Six Meridians Syndrome Differentiation Standard,and then collate all the data information in the DD Six Meridians Syndrome Differentiation Questionnaire into Excel.After checking the data information,use SPSS26.0 software to analyze and obtain the distribution law of the Six Meridians Syndrome Differentiation of DD.Results:1.A total of 101 DD patients were collected in this study.In terms of gender,male accounted for 54.46%and female accounted for 45.54%;In terms of age,the youth group accounts for16.83%,the middle-aged group accounts for 50.50%,and the elderly group accounts for32.67%;In terms of the course of DM,28.71%of patients have a course of 1-5 years,34.65%have a course of 6-15 years,and 36.63%have a course of>15 years;In terms of BMI,patients with a BMI less than 18.5kg/m2 accounted for 0.99%;23.76%of patients with a BMI<24kg/m2≤18.5kg/m2;48.51%of patients with a BMI<28kg/m2≤24kg/m2;26.73%of patients have a BMI≥28kg/m2.2.This study identified a total of 7 types of six meridian diseases,including 3 types of single meridian diseases（accounting for 60.40%）and 4 types of two meridian diseases（accounting for 39.60%）.In terms of the distribution pattern of single meridian diseases,the main diseases are Taiyin meridian diseases（accounting for 27.72%）,Shaoyin meridian diseases（accounting for 17.82%）,and Jueyin meridian diseases（accounting for 14.85%）;From the distribution pattern of the two meridian diseases,the main syndromes are Taiyin Shaoyin OECD syndrome（accounting for 17.82%）and Taiyang Yangming OECD syndrome（accounting for13.86%）.In terms of the six meridian diseases after separation,the main type is the Taiyin meridian disease,with a total of 46 cases,accounting for 32.64%.3.There was a statistically significant difference in the distribution of age and six meridian diseases among DD patients（P<0.05）.The young group of patients mainly had the syndrome of Taiyangming and economic growth,accounting for 52.94%.The middle-aged group of patients mainly had the syndrome of Taiyin meridian,accounting for 41.18%.The elderly group of patients mainly had the syndrome of Jueyin meridian,accounting for 36.36%.4.There was a statistically significant difference in the distribution of disease course and six meridian syndrome between DD patients（P<0.05）.DD patients with a disease course of 1-5years were mainly diagnosed with Taiyin meridian syndrome（55.17%）;DD patients with a disease course of 6-15 years are mainly characterized by Shaoyin Meridian syndrome（40.00%）;The majority of DD patients with a DM course of more than 15 years were diagnosed with Jueyin Meridian Syndrome（35.14%）.5.There was a statistically significant difference in the distribution of BMI and six meridian syndrome（P<0.05）.One DD patient with a BMI<18.5 kg/m2 was classified as the Sun Yang Ming OECD syndrome;The main type of DD patients with 18.5kg/m2≤BMI<24 kg/m2 is Taiyin meridian syndrome,accounting for 45.83%;DD patients with 24 kg/m2≤BMI<28kg/m2 were mainly characterized by Shaoyin Meridian syndrome,accounting for 26.53%;DD patients with a BMI≥28 kg/m2 belong to the Taiyin Meridian Syndrome and Jueyin Meridian Syndrome,each accounting for 29.63%.6.There was a statistically significant difference in the distribution of C-peptide and six meridian syndrome in DD patients（P<0.05）.Patients with an empty stomach C-peptide of0-1ng/ml were mainly diagnosed with Shaoyin meridian syndrome,accounting for 36.11%.Patients with an empty stomach C-peptide of 1-2ng/ml were mainly diagnosed with Taiyin meridian syndrome,accounting for 43.75%.Patients with an empty stomach C-peptide of>2ng/ml were mainly diagnosed with Taiyangming OECD syndrome,accounting for52.94%.There was no statistically significant difference in gender,Hb A1C,and distribution of six meridian diseases in DD patients（P>0.05）.Conclusion:1.The six-channel syndrome differentiation system is used to guide the clinical treatment of DD.Among them,patients with older age,longer duration of DM,overweight,normal weight,and poor islet function can be treated from the Taiyin channel,Shaoyin channel and Jueyin channel;Young patients with DM,short course of disease,emaciation and moderate islet function can be treated from Yangming disease.2.The distribution of the six meridian syndromes of DD is affected by age,the course of DM,BMI,fasting C-peptide and other levels.The change level of the above factors can reflect the change characteristics of the six meridian syndromes from the outside to the inside,from yang to yin,and from light to heavy.3.When clinical application of syndrome differentiation of six meridians to treat DD,attention should be paid to the mastery of disease nature,disease location and transmission characteristics.