The Study Of The Protective Mechanism Of Xiengyangkeli With Yohimbin On Kidney Yang Deficiency Animal

Today, there are many specific medicines for curing ED. But, it still can't satisfy the increasingdemands for ED patients.My professor,Li Yueqing raises the importance of treating ED from Kidneyand Liver, and adopts the view of combining TCM and western medicine. A Formula ofXiengyangkeli with Yohimbin (corynine), hope it can achieve the supplementary result. This studyobserves the general pharmacology of Xiengyangkeli with Yohimbin. To study the protectivemechanisms of kidney yang deficiency rodent models.And by using RIA to measure the effect on thesex hormone level of kidney yang deficiency rodent model.PartI The effects of XYKL with Yohimbin on kidney yang deficiency rodent models.Experiment 1 By using DigBehv, an auto active analyzing system, to observe the effect of XYKL withYohimbin on kidney yang deficiency rodent models. The results show that by comparing with thenormal group, the small dosage rodent group's the total distance, active time, crossing time are allrelevant decreased theaverage velocity is lower, the number ofactivitytime has increased, theresttime has shortened,P<0.05 or 0.01. By comparing XYKL only and the large and medium dosage groups of XYKL with Yohimbin,all indicators are higher than XYKL only. By comparing Yohimbin only with large and mediumdosage groups,all indicators are still relatively higher than Yohimbinonly group.Experiment 2 The effects of XYKL with Yohimbin on kidney yang deficiency rodent models'cold resistance.By observing the effects of XYKL with Yohimbin on kidney yang deficiency rodent models'coldresistance. The result shows comparing with the normal group and XYKL with Yohimbin large,mediumand small dosage rodent groups also increased the cold resistance time, P<0.05 or 0.01.Thecomparison of Yohimbin only group with XYKL with Yohimbin large,medium dosage rodent groupshave also increased the cold resistance time, P<0.05. The comparison of XYKL only group withXYKL with Yohimbin large dosage rodent group has showed a relevant increase on the coldresistancetime,P<0.05.Experiment3 The effects of XYKL with Yohimbin on kidney yang deficiency rodent models' swimmingability. By observing the effects of XYKL with Yohimbin on kidney yang deficiency rodent models'swimming ability. . The results shows comparing with the normal group and XYKLwith Yohimbinlarge,medium and small dosage rodent groups also increased the swimming ability.(P<0.05 or 0.01)The comparison of Yohimbin only group with XYKLwith Yohimbin large, medium dosage rodentgroups have also increased the swimming ability..( P<0.05 ) The comparison of XYKL only groupwith XYKL with Yohimbin large dosage rodent group has showed a relevant increase on theswimming ability.(P<0.05)Experiment 4 The effects of XYKL with Yohimbin on kidney yang deficiency rodent models' mattingability.By observing the effects of XYKL with Yohimbin on kidney yang deficiency rodent models'mating ability..The results show that by comparing with the normal group and the control group,thecontrol group has delayed the first catching time and the first ejaculation time.The number of catchingtime and the number of ejaculation time have decreased. The comparison of XYKL with Yohimbinlarge, medium small dosage, Yohimbin only and XYKL only group. The control group has shortenthe first catching time and the first ejaculation time, thenumber ofthe catching time and the numberof ejaculation time have increased, P<0.05 or 0.01. The comparison of Yohimbin only, XYK Lonly,XYKL with Yohimbin small dosage rodent groups,XYKL only,XYKL with Yohimbin small dosagerodent groups has not indicated a significant change. But, XYKL with Yohimbin large and mediumdosage rodent groups has showed a better indicator than Yohimbin only group,by comparing XYKLonly group with the XYKL with Yohimbin large dosage group, the XYKL with Yohimbin largedosage group has better indicators than the XYKL only group,P<0.05.Part II The effects of XYKL with Yohimbin on kidney yang deficiency rodent models, whichcaused by Adenine.Experiment 1 The effects of XYKL with Yohimbin on...