| Objective Through a retrospective case-control study, observe the changes inserum lipids in the vocal cord polyp patients, to explore the changes of blood lipid andits correlation in polyp of vocal cord.Method From2010January to2012December in the First Affiliated Hospital ofFujian Medical University during the period of Otolaryngology diagnosis for patientswith vocal cord polyps as the experimental group, the control group from2010January to2012December in the First Affiliated Hospital of Fujian MedicalUniversity during the examination of normal human. Determination of serum totalcholesterol (TC), triglyceride (TG), high density lipoprotein cholesterol (HDL-C), lowdensity lipoprotein cholesterol (LDL-C), apolipoprotein A-I (ApoA-I). Data usesSPSS18.0statistical software to analyze the experiment group and control group data,calculate the P value (P<0.05is significant difference).Result There are significant differences ApoA-I non smoking group and nonsmoking normal vocal cord polyp group HDL-C, male group (P<0.05); HDL-C hadstatistical significance, smoking group and non smoking vocal cord polyp of vocalcord polyps in group ApoA-I (P<0.05); the difference was statistically significantpolyps vocal and smoking smoking normal group differences (P<0.05), ApoA-IHDL-C difference was not statistically significant (P>0.05); normal non smokinggroup and normal people smoking group HDL-C, ApoA-I had significant difference(P<0.05). Statistical significance of vocal cord polyp group and normal group ApoA-Idifferences in the female group (P<0.05HDL-C), the difference was not statisticallysignificant (P>0.05). HDL-C, ApoA-I Logistic regression analysis showed thatApoA-I was negatively correlated with vocal cord polyps (r=-3.742, OR=0.024,P<0.05), the correlation between HDL-C and polyp of vocal cord was not statisticallysignificant (P>0.05).Conclusion ApoA-I in serum of patients with vocal cord polyp decline; ApoA-Iand vocal cord polyp formation exist certain correlation. |
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