The Clinical Observationon On The Therapeutic Effect Of YiQiHuoXue Decotion In The Treatment Of The Elderly "H" Hypertension (Qi Deficiency And Blood Stasis)

Objective: To observe the effect of YiQiHuoXue decoction combined with medicine inthe treatment of elderly "H" hypertension (qi deficiency and blood stasis) on blood pressure,TCM syndrome, hypertensive patients’ quality of life, level of homocysteine, comparison theclinical effect between treatment group and control group before and after treatment.Method:1. Randomly divided96elderly "H" hypertension (qi deficiency and bloodstasis) patients who were matched inclusive criteria into treatment group48cases and controlgroup48cases.2. The treatment group: treated with YiQiHuoXue decoction Combined withamlodipine besylate，hydrochlorothiazide tablets and folite tablets. Control group: treated withamlodipine besylate，hydrochlorothiazide tablets and folite tablets.3. After four weeks,observation blood pressure, TCM symptoms, score of hypertensive patients’ quality of life,homocysteine levels and changes of liver and kidney function, Serum potassium levels safetyindex before and after treatment，to determine the clinical curative effect.Results:1. Comparison of consulting room blood pressure measurement(CBP) andambulatory blood pressure monitoring(ABPM): two groups blood pressure are significantlylower than before treatment; Consulting room blood pressure in treatment group than thecontrol group decreased significantly, the diastolic blood pressure have no difference betweentwo groups;Ambulatory blood pressure monitoring of nighttime systolic blood pressuremean(nSBP) and daytime diasolieb blood Pressure mean (dDBP) treatment group is betterthan the control group (P<0.05).2. Comparison of efficient and target achievement of bloodpressure: the total effective rate of consulting room pressure measurement, the treatmentgroup (91%) is better than the control group (81%); the compliance rate of ambulatory bloodpressure, the treatment group (87%) is better than the control group (75%).3. Comparison ofTCM syndromes: the scores of all items in the treatment group were increased after treatment(P<0.05), dizziness, headache of the control group was statistically significant (P<0.05); therehave statistical significant of the total score between two groups (P<0.001).4. Comparison oftraditional symptoms of clinical efficacy: results the validity rate of treatment group is44cases (91%), which is obviously prior to the contrast one that is30cases (63%).5.Comparison of hypertensive patients’ quality of life: two groups of multi dimensions aresignificantly improved, but the treatment group was significantly better than the control group.6. through statistical analysis there have correlation with TCM symptoms of hypertension andthe quality of life.7. Comparison of HCY: two sets of values are falling, the treatment group is better than the control group.8. Comparison of safety indicators: there is no differencebetween two groups After treatment (P>0.05).Conclusion: Through the above study, the treatment group were obviously superior tothe control group in the treatment of elderly "H" hypertensive (qi deficiency and blood stasis),on the control of blood pressure levels, improve TCM symptoms, hypertensive patients’quality of lif and lowering homocysteine value, less adverse reaction, the use of safe.