Retrospective Analysis Of 108 Cases Of White Abscess Due To Blood-heat Syndrom

Purpose:Through summarizing the medical records of patients with common psoriasis who underwent TCM clinical pathway management,understanding their clinical treatment,analyzing the general clinical characteristics,pathogenesis pattern and combined Chinese and Western medicine treatment,etc.,and summarizing the treatment experience,we can provide reference and reference for further optimizing the prevention and combined Chinese and Western medicine standardized treatment plan for this disease.Material and method:By retrospectively analyzing patients with common psoriasis with blood-heat evidence who were treated in the dermatology ward of the Affiliated Hospital of Liaoning University of Chinese Medicine from January 2021 to December 2022,and their medical records were analyzed by using SPSS statistical software to summarize relevant clinical experience and provide basis and consideration for disease prevention and treatment.Results:1.General situation: A total of 108 patients were treated in this study,the ratio of male to female was 2.09:1,the initial age was 42.59±18.65 years old,mainly young and middle-aged people,with an average course of disease of 10.58±11.02 years,of which the majority was1-10 years(43 cases,39.81%).Spring and autumn were the most common seasons(71 cases,65.74%).BMI showed that 45 cases(41.67%)were overweight and obese.Eight patients(7.40%)had a family history of psoriasis.2.Inducing factors: 37 patients(34.26%)had definite inducing factors,of which infection was the main inducing factor.24 patients(22.22%)had a history of smoking,and 26 patients(24.07%)drank alcohol.The course of disease of patients with smoking history was longer than that of patients without smoking history.3.Complications: 53 patients(49.07%)were accompanied by one or more complications,mainly hypertension,diabetes,coronary heart disease,dyslipidemia and other diseases.The age of onset in the group without complications was younger than that in the group with complications.4.Clinical manifestations: The skin lesions are widely distributed,mostly involving the whole body,and the order of the first part is limbs,scalp,and trunk.Most of the patients had skin itching,64 patients(59.26%)had itching degree that affected sleep,15 patients(13.89%)had fingernail(toenail)changes,and the patients with nail changes mainly had scalp at the first time,and the severity of the disease was even worse.5.TCM treatment: In this study a total of 103 oral herbal tonics were collected,the traditional Chinese medicine prescriptions were mainly heat-clearing and detoxicating,blood-cooling and hemostasis drugs,and were also used to dissipate blood stasis,generate fluid,promote blood circulation,dry and damp,and tonify.The choice of drugs is based on bitter cold,which is mainly mild cold,mild,sweet and spicy,and mainly belongs to liver,heart and lung meridians;The drug association analysis showed that the core drugs were mainly concentrated among raw rehmannia,liquorice,Rhizoma,peony bark,caulis spatholobi and sophora japonica;Cluster analysis of the top 24 herbs was clustered into 4 categories,the first :Rhizoma,Sophora japonica,Radix arnebiae seu lithospermi,Caulis spatholobi,Forsythia,Honeysuckle,White Flower and Snake Tongue Herb,Cortex moutan,Radix paeoniae rubra,Raw radix rehmanniae,Salviae Miltiorrhizae,Scutellaria barbata,and Fructus Mume.the second : Scrophularia,Cortex dictamni,Schizonepeta,Tribulus terrestris,liquorice.the third :Silybum marianum,bitter ginseng,Tu Fu Ling.the fourth : Atractylodes macrocephala,Poria,Yunzhi.6.Efficacy evaluation: After treatment with integrated traditional Chinese and Western medicine,the patient’s PASI score was 10.50±3.59,and the TCM syndrome score was 3.64±1.57,which was significantly lower than before treatment.The clinical effect is significant,and the total effective rate of treatment is 98.15%.Conclusion:1.In this study,men were more likely to suffer from blood-heat evidence of psoriasis than women,where the age of first onset was predominantly young and middle-aged,with a longer disease duration,mostly in spring and autumn.2.In this study,the proportion of patients with psoriasis comorbidities is high,the pathogenesis of comorbidities is complex,and there may be a common pathogenic pathway between psoriasis and psoriasis,and the two are closely related.3.In this study,the initial skin lesions of psoriasis mostly occurred in the limbs,often affecting the entire body.The main pathogenic factor is infection,and its incidence is also related to BMI,smoking,and alcohol consumption.4.The drugs were classified into four categories by cluster analysis,of which the first category can prevent the transformation to blood stasis syndrome and blood dryness syndrome while treating blood heat syndrome;The second type of drugs is applicable to those with severe pruritus of psoriasis with blood heat;The third kind of drugs is suitable for patients with blood heat syndrome and severe damp-heat;The fourth class of drugs is applicable to patients with spleen deficiency and dampness due to blood heat syndrome.5.In this study,the treatment of psoriasis vulgaris hemofever adopts the method of combination of traditional Chinese and western medicine and both internal and external treatment.The effect is relatively rapid and significant.