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Study On Relationship Between Coronary Arteriography,the Levels Of Hcy And Hs-CRP And TCM Syndrome Differentiation-type In Coronary Heart Disease

Posted on:2005-01-19Degree:DoctorType:Dissertation
Country:ChinaCandidate:S Q XiongFull Text:PDF
GTID:1104360125468202Subject:Traditional Chinese Medicine
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Part One: Relationship between Coronary Arteriography and TCM Syndrome Differentiation-type in Coronary Heart DiseaseObjective: To study the relationship between severity and form of coronary artery lesion and TCM Syndrome Differentiation-type(TCM-SDT) and various degree Blood-stasis Syndrome with CHD.Methods: 1. 285 patients with CHD who were finally diagnosed by CAG were selected and their results of CAG were analyzed, which involved number, severity, form and Gensini score of coronary artery lesion. Two methods were adopted to analyse the form of coronary artery lesion: Form of coronary artery lesion was divided into A type, B type and C type according to ACC/AHA criteria; Coronary artery stenosis (its stenosis 50%and <100%) was divided into I type, II type and III type according to its form. 2. All patients' TCM-SDT was differentiated by adopting the standard of Syndrome Differentiation for coronary artery diseases revised in 1991. All 285 patients had secondary Excess Syndrome, among them 42 patients with Blood stasis Syndrome, 69 with Qi stagnation-Blood stasis Syndrome, 65 with Phlegm Turbid-Blood stasis Syndrome, 78 with Phlegm heat-Blood stasis Syndrome, and 31 with Cold condensation-Blood stasis Syndrome. 259 patients with obvious primary Deficiency Syndrome, among them 136 were Qi-Deficiency, 62 Yin-Deficiency, 38Yang-Deficiency, and 23 Yang-collapse. Patients' Blood stasis Syndrome was also differentiated to slight, secondary and serious according to scoring measure which was formulated by ourselves, among them 84 with slight, 108 with secondary, and 93 with serious. 3. Subsequent statistic processing included chi-square test and analysis of variance.Results:1. Correlation between CAG results and secondary Excess Syndrome in TCM-SDT of CHD(1) Relationship between number and severity of coronary artery lesion and TCM secondary Excess SyndromeThere were significant differences in the distribution of coronary artery lesion number among secondary Excess Syndrome groups(X=50.366, P<0.001). One-artery lesion constituted the majorty in Blood stasis Syndrome group(52.4%) and Qi stagnation-Blood stasis Syndrome group(60.9%), while three-artery lesion was the most in Phlegm Turbid-Blood stasis Syndrome group(49.2%), Phlegm heat-Blood stasis Syndrome group(45.6%) and Cold condensation-Blood stasis Syndrome group(54.8%). From Qi stagnation-Blood stasis Syndrome group(1.55), Blood stasis Syndrome group(1.67), Phlegm heat-Blood stasis Syndrome group(2.24), Phlegm Turbid-Blood stasis Syndrome group(2.25) to Cold condensation-Blood stasis Syndrome group(2.42), average number of coronary artery lesion increased one by one, but there were no significant differences. There were significant differences in Gensini score among secondary Excess Syndrome groups (F=9.149, P0.001). Gensini score of Phlegm Turbid-Blood stasis Syndrome group was higher than that of Blood stasis Syndrome group and Qi stagnation-Blood stasis Syndrome group(all P<0.05); Gensini score of Phlegm heat-Blood stasis Syndrome group and Cold condensation-Blood stasis Syndrome group was also higher than that of Blood stasis Syndrome group and Qi stagnation-Blood stasis Syndrome group(all P<0.01).(2) Relationship between ACC/AHA type or form of coronary artery lesion and TCM secondary Excess SyndromeThere were significant differences in the distribution of coronary artery lesion ACC/ AHA type among secondary Excess Syndrome groups(X=38.881, P0.001). A type lesion(38.1%) and B type lesion(42.9%) constituted the majority in Blood stasis Syndrome group; A type lesion(47.8%) and B type lesion (43.5%) also constituted the majority in Qi stagnation-Blood stasis Syndrome group; B type lesion(51.3%) ranked first in Phlegm heat-Blood stasis Syndrome group; while C type lesion was the most in Phlegm Turbid-Blood stasis Syndrome group(44.6%) and Cold condensation-Blood stasis Syndrome group(48.2%). There were also significant differences in the distribution of coronary artery stenosis type among secondary Excess Syndrome groups(X=73.64...
Keywords/Search Tags:atherosclerosis, coronary arteriography, coronary heart disease, TCM Syndrome Differentiation-type
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