The Study On The Clinical Effect Of Mahuang Lianyao Chixiaodou Tang To Cure Chronic Nephritis And The Antiproliferation Results To Intercapillary Cells

MaHuangLianYaoChixiaodou Tang was used to cure interior stagnation of heat In ShanHanLun, but hereditary physician use this formula to cure jaundice and dropsy. No matter how the hereditary physician uses this formula to cure, they all have the same pathogenesis, which is damp-heat gluing each other. So if the pathogenesis of the illness is the pathogenic heat takes up with the damp pathogen dampness, the MaHuangLianYaoChixiaodou Tang can be used to cure illness.On the basis of this knowledge, indication of diaphoresis relieving superficies method was discussed. The diaphoresis relieving superficies method was used to cure diseases caused by exogenous pathogenic factor and internal injury. The diaphoresis relieving superficies method was used to cure diseases of muscle and skin, and sweat pore, and bones and muscles, and porus sudoriferus and striae of the skin. The diaphoresis relieving superficies method was used to cure diseases caused by wind-cold or retention of fluid in the body, also can by yingqi and weiqi estranged. The diaphoresis relieving superficies method was used to cure diseases of pain caused by damp pathogen distressed.Moreover MaHuangLianYaoChixiaodou Tang has the special compatibility law. MaHuang can induce sweat and dispelling exogenous evils to eliminate the moist heat on the skin. XingRen, together with MaHuang can revert the function of lung-qi to regulating fluid passage and eliminate moist heat.At the same time, the clinical research discovered that MaHuang LianYao Chi xiaodou Tang can cure chronic nephritis. After the treatment, the complement three and IgG can improved. It illustrates that MaHuang LianYao Chi xiaodou Tang has the regulate result to regulate the humoral-mediated immunity function. The research indicates the formular has the function to improve the clinical symptom, and to decrease urine protein, and to raise plasma albumin.Furthermore, empirical study illustrates that MaHuangLianYaoChixiaodou Tang also have the direct repression results on Mesangial cell. It illustrates the effect mechanism of MaHuangLianYaoChixiaodou Tang to cure chronic nephritis. The result indicates this formula have the direct repression results on rat Mesangial cell (HBZY-1), and the results improved with the density increased. The result was came true by the formula inhibit the correlate cytokine secrete by the HBZY-1. At the same time, the formula induces HBZY-1 to apoptosis. The result was came true by the formula inhibit the expression of apoptosis controlling gene.