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Based On The Twin Child's Personality, Mental Health Study Of, And Not Through The Five Senses Channel Exchange Phenomenon

Posted on:2010-03-22Degree:DoctorType:Dissertation
Country:ChinaCandidate:Y X FuFull Text:PDF
GTID:1115360278959603Subject:Biomedical IT
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Objective: To estimate the heritability of personality and mental health of children by using a twin design method of quantitative genetic analysis. To introduce some questionnaires related to family environment such as PSDQ,FAD-GFS,SLE,FSQ,FLQ,EFQ and evaluate their validity and reliability. To analysis the influences of family environment on children personality and mental health. To compare the personality and mental health between the twin child and that of the-only child.Methods:Using cross-sectional design,twins and only children aged 6-16years were recruited. Using SDQ which was examined by parents and children(>=11)to evaluate the children mental health and using EPQ applying on children to evaluate the children personality. The general questionnaire,PSDQ,FAD-GFS,SLE,FSQ,FLQ,EFQ were used to collect information about family environment from parents. Zygosity was determined by the DNA picked up from cheek mucosa of twins children. Holzinger analysis was employed to estimate the heritability of personality and mental health. The stastic methods include t-test, nonparametric test, pearson correlation, spearman correlation, Chi-square, confirmatory factor analysis etc.Results: 122 pairs(244 children) of twins (103 twin pairs DNA were picked up successfully, including 54 MZ twin pairs and 49 DZ twin pairs and 504 only children were participated in this study. The heritability of personality:N:0.71,P:0.56,L:0.43,E:0.07.The heritability of mental health: emot: 0.86, hyper:0.75,total:0.61,cond:0.4,proso: 0.12,peer: -0.97The reliability and validity of PSDQ,FAD-GFS,SLE,FSQ,FLQ,EFQ is: Cronbach coefficient were 0.626 to 0.884; retest reliability were 0.537 to 0.901 ; The scores of the scale in those questionaires were correlated with each factor significantly and the coefficient of correlation is more than those between each factor of those scales.The correlation between the scores of FSQ,EFQ and the scores of Index of General Affect was-0.192,0.539; The correlation between the scores of FAD-GFS,FLQ(the score of total and three factor differently) and the scores of family cohesion scores(FACESII-CV) was -0.423,0.237,0.514,0.302,0.210. Maker of confirmatory factor analysis show met the criteria standard for adequacy of fit. ( CMIN/df: 2.218-3.745; TLI: 0.808-0.920; RMSEA: 0.052-0.079; MECVI of default model is very close to that of saturated model, most of proliferation index are more than 0.8)In twins family,the score of FAD-GFS was significantly correlated with EPQ-E, proso of SDQ(r=-0.235,-0.200),the score of FSQ,EFQ was significantly correlated with total score of SDQ(r=0.206,-0.304),FLQ was significantly correlated with EPQ-n,total,proso of SDQ, the score of father authoritative parenting style was significantly correlated with EPQ-p,total, proso of SDQ(r=-0.196, -0.244,0.207),the score of mather authoritative parenting style was significantly correlated with EPQ-e,total,proso of SDQ(r=0.230,-0.437, 0.342). the score of family cohesion was significantly correlated with EPQ-n,total proso of SDQ(r=0.198,-0.315,0.432), the score of family adaptability was significantly correlated with total,proso score of SDQ(r=-0.359, 0.357).In only-child family, standardized regression equation of family environment influence on children personality and mental health:EPQ-p=0.087*sle+0.207*father autocratic parenting+0.131*educational of father + 0.110 *family type -0.110*role of discipline-0.080*parental attitude+0.087* family adaptability; EPQ-e=0.105*EFQ -0.088* SLE- 0.101 * family income; EPQ-n=0.143*SLE-0.090*family cohesion+0.089* family income +0.117 *the attitude of the old-0.138*the role of child experiments of FLQ-0.101* parents shaping the behavior of children of FLQ;EPQ– l = - 0.136* SLE - 0.093* relationship between parents -0.155*attitude of the old;SDQ– total = 0.142 *FAD+0.160*father autocratic parenting+0.230* father free parenting + 0.164*mother autocratic parenting -0.072*education of father,SDQ– peer=0.127*family cohesion +0.147* family adaptability - 0.152*father autocratic parenting -0.100 * family type+ 0.095*EFQ - 0.111*the difference between the real and the ideal of family cohesion。The scores of four dimension of EPQ and five factor of SDQ have significant difference(Except for inattention-hyperactivity factor) between twin child and only child, the scores of EFQ,FLQ,FACESII–CV, FSQ, FAD-GFS have significant difference between the twins children family and the only child family.Conclusion: Genetic factor contributed to Neuroticism most. Genetic factors and environment factor play an equal role in Psychoticism and Lie, but Extroversion-Introversion was mainly influenced by environment factors. Emotional problems were influenced by genetic factors most,followed by inattention-hyperactivity problems and total difficulties ,environment factors play a main role in conduct problems and prosocial degree while peer problems were only influenced by environment factorsPSDQ,FAD-GFS,SLE,FSQ,FLQ,EFQ has good reliability and validity, in line with requirements of psychometric and is useful as a tool to evaluate the family environment.Each aspect of family environment, influence children personality and mental differently。Except for inattention-hyperactivity problems, there is obvious different in children personality,mental health and their family environment between twin and only-child. The study of twins:Objective: To investigate whether communication phenomenon ,NOT through conventional sense such as look,listen,touch,smell,taste,exists and explore the influence of genetic and environmental factors on this phenomenon through conducting card-guessing tests on twins.Methods: After twin children aged between 6 and 16 years, who still live together, are recruited, the number of correct hits in guessing the cards in twins is compared with those expected by chance. Buccal mucosa samples were collected from all twins for DNA extraction and zygosity identification test. Twins are divided into MZ twin group and DZ twin group according to their zygotic identity. Card-guessing tests are performed to compare the number of correct hits in twins between the MZ and DZ.Results: The number of correct hits in twins is greater than those expected by chance, and the number of correct hits in MZ twins is greater than those in DZ twins which has no significant difference.Conclusion: The communication phenomenon NOT through conventional sense may exist. The presence of this phenomenon may be contributed to similar genetic basis and living in the same environment ,the two of which has no difference。ERP study of adult:Objective: To demonstrate whether communication phenomenon of brain electrical activity, related to emotional or cognitive content, between two adults individual (named as SENDER and RECEIVER) exists.Methods: Applying high density ERP technique, using CAPS,letter pictures,CAFPS as stimuli,compare the information of ERP differences on RECEIVER at the same time the SENDER perform a standard categorization task which lead to significant difference in ERP.Results: The ERP of SENDER show difference significantly in the s1(neutral pictures),s2(extremely negative pictures)and s3(letter pictures),simultaneously, under the different stimuli of SENDER ,The ERP of RECEIVER show that there is the significant difference in late potentials between s2 and s1, between s2 and s3 which may be much wider. There is no difference between happy face,sad face,angry face pictures in ERP of RECEIVER.Conclusion: The communication between brain electrical activity of two separated subjects isolated from five sensory channels may occur ,it may occur at the same time or delay, Cognitive and emotional experience may arouse electrical activity of different brain region, the detail of communication tend to affective content about self– experience EEG study of SD rats:Objective: To demonstrate whether the communication between two SD rats base on the similar genetic basis or the same living environment, who separated from each other, occurs.Methods: One SD rat(RECEIVER) was examined by EEG spectral analysis and ECG analysis under anesthesia while the other SD rat(SENDER) received optimal stimuli or malignant stimuli .the course was conducted in the shielded and the unshielded. Compare the EEG and ECG of RECEIVER between the stimulation state and resting state of SENDER.Results: This study show no significant difference in EEG(index: percentile weight and average weight of EEG on frontal lobe, temporal lobe, hippocampus of each frequency band) and ECG(index: R,PR segment,ST segment,QRS segment,QT segment) of RECEIVER during the time that the SENDER suffered from malignant stimulation,experienced optimal stimulation and of resting state.Conclusion :The communication of SD rats, not through common five sense organ,may not exist, even though the same genetic basis or the common living surrounding.The optimal stimuli and the malignant stimuli of SENDER cannot influence the EEG of Frontal lobe, temporal lobe, hippocampus and ECG on RECEIVER. There is no sufficient evidence for the existence of this communication of animal.
Keywords/Search Tags:Twin stuty, children, Personality, Mental health, Family environment, Communication phenomenon, ERP, EEG
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