A Study On Exercise Prescription For Middle-aged People Of Dyslipidemia

A Study on Exercise Prescription for Middle-aged People of Dyslipidemia Post-graduate Student: Zhang Peizhen Tutor: Prof. Tian Ye Dyslipidemia is the first risk factor of coronary heart disease, especially among themiddle-aged people. Thus, it is always the focus of sports medicine research to prevent and treatdyslipidemia and coronary heart disease (CHD) by different safe and effective methods. As asecure and efficacious method for the treatment and prevention of dyslipidemia, exercise therapyis increasingly attracting the attention of experts and researchers in the world. But, up to now,there is so few studies of exercise treating of dyslipidemia. This dissertation attempts to find asuitable exercise project for the treatment of dyslipidemia. We study the effects of variousexercise projects on middle-aged people of dyslipidemia. Moreover, we also determine some ofapolipoprotein gene polymorphism by means of molecular biology and probe into their effect onthe treatment of dyslipidemia through exercise. First, through questionnaire and screening, we pick out 120 middle-aged (50～70 years old)people of dyslipidemia and determine their functional capacity (F.C.) by maximal cycleergometer exercise testing. Then, we draft the exercise prescription. We use walking-runningexercise and Taijiquan as main exercise methods. The scope of exercise intensity was 50～70%F.C.. They do exercises one time a day, 30～60mins per time, 5 days a week, and two months orsix months for one exercise cycle. Different methods, different intensities (50～59%F.C., 60～70%F.C.), and different duration constitute different exercise projects. We observe the blood lipidindexes' and related functions' improvement resulted from different exercise prescription. Themain indexes include blood lipid metabolism, cardiopulmonary function, body fat distributionand body composition, and apolipoprotein gene polymorphism. The conclusions are as following: (1) Walking-running exercise is an effective exercise method for treatment of dyslipidemiain middle-aged people. During walking-running exercises, exercise intensity is not the mainfactor affecting on treatment effect of dyslipidemia, duration is more important one. A morecomprehensive improvement of blood lipid will appear after longer exercise period. So, oneshould stick to exercise. (2) After the walking-running exercise, the improvement of serum lipoprotein appearsearlier than that of serum apolipoprotein. In serum lipoprotein, the improvement of high densitylipoprotein cholesterol (HDL-C) appears earliest; and the improvement of low density lipoprotein IV北京体育大学 2004 届博士研究生学位(毕业)论文cholesterol (LDL-C) will appear after long-period exercise. It is the first time to observe theexercise's effect on apolipoprotein E (apoE). We find that after a long-period (6 months)walking-running exercise, serum apoE level will increase. In addition to improvement ofdyslipidemia, walking-running exercise can also resist the decreasing of serum estrogen withaging in post menopausal women. (3) Walking-running exercise can also improve the cardiopulmonary function ofmiddle-aged dyslipidemia patient. Walking-running exercise of 50～59%F.C. intensity can helpthem to keep the cardiac functional capacity and decrease the resting heart rate and systolic bloodpressure. The walking-running exercise of 60～70%F.C. intensity can increase cardiac functionalcapacity. Both of the intensities can increase vital capacity. (4) The walking-running exercise of two months can not improve body compositioneffectively, it can improve body fat distribution of dyslipidemia patient, reduce abdominal fatclustering, and decrease the risk of CHD. The walking-running exercise of six months canimprove body composition efficaciously, reduce body fat weight, increase muscle weight, andstrengthen patien...