| Arachis hypogaea L. (Leguminosae) is a folk medicine for the treatment of a variety of human diseases, such as insomnia, hypertension, children’s crying in the night, brain arteriosclerosis and tracheitis. A chemical investigation on Arachis hypogaea L. resulted in the isolation of 67 compounds. 59 of them were identified as 6H-benzofuro[3,2-c][1] benzopyran-6-one-3,9-dihydroxy-4,8-dimethoxy(1) , pongacoumestan(2) , sativol (3) , 3’-methoxycoumestrol (4) , 4’-methoxycoumestrol (5) , cichorigenin( 6 ) , 5,6-dimethoxy-coumarin ( 7 ) , cichorioside ( 8 ) , sativanone ( 9 ) , 7,4-dihydroxy-2’,5’-methoxyisoflavone (10) , 7,4’-dihydroxy-,3’-methoxyisoflavone (11) , cladrin (12) , 7-hydroxy-2’,5’-methoxyisoflavone (13) , 7,4’-dihydroxyisoflavone (14) , flavosil (15) , 5-methoxy-isolarisiresinol (16) , isolariciresinol (17) , cimicifugic acid(18) , syringaresinol (19) , acanthoside B (20) , ferulic acid (21) , 4-methoxycinnamic acid (22) , 4-hydroxycinnamic acid (23) , vanillic acid (24) , 4-methoxybenzoic acid(25) , 4-hydroxybenzoic acid (26) , 2-hydroxybenzoic acid (27) , nicotinic acid (28) , 2-furancarboxylic acid (29) , protocatechuic acid (30) , wobezit DM (31) , syringoside(32) , L-(-)-phenylalanine(33) , cyclo(L-Leu-L-Tyr) (34) , cyclo(L-phenylalanyl-L-tyrosyl)(35) , cyclo(L-phenylalanyl-L-phenylalanyl) (36) , cyclo(L-Pro-L-Tyr) (37) , cyclo(L-Phe-L-Leu) (38) , cyclo(Gly-L-Phe) (39) , cyclo(L-alanyl-L-phenylalanyl) (40) , cyclo(L-Pro-L-Leu)(41) , cyclo(L-prolyl-L-valyl) (42) , JBP 485 (43) , cyclo(L-alanyl-L-leucyl) (44) , (3S-cis)-3-(hydroxymethyl)-6-(2-methylpropyl)-2,5-piperazinedione (45) , cyclo(L-leucyl-L-leucyl) (46) , thymidine (47) , thymine (48) , uracil (49) , D-2-O-methyl-myo-inositol(50) , amber acid (51) , methyl hydrogen succinate (52) , arachisalactone (53) , arachisalol ( 54 ) , corchoionol C ( 55 ) , isololiolide ( 56 ) , 3β,16α,24-trihydroxy-olean-12-en-28-oic acid (57) , 3β,24-dihydroxyolean-12-ene (58) , daucosterol (59) . Among them, 1 was a new compounds.R. ellipticus Smith var. obcordatus Focke is a shrub, belonging to the family Rosaceae, which is commonly distributed in Sichuan, Yunan, Shanxi, Guizhou Province in China. Different parts of the plant have been widely used as folk medicines for the treatment of a variety of human diseases, such as detumescence, acesodyne, detoxifcation, treatment of bacterial dysentery, tonsillitis, icteric hepatitis. A chemical investigation on R. ellipticus Smith var. obcordatus Focke resulted in the isolation of 33 compounds. 23 of them were identified as rubuside A (R1) , rubuside B (R2) , rubuside C (R3) , rubuside D (R4) , alpinoside (R5) , rubuside E (R6) , rubuside F (R7) , rubuside G (R8) , rubuside H (R9) , 2α,3β,23-trihydroxyurs-12,18-dien-28-oic acid 28-O-β-D-glucopyranosyl ester (R10) , 2α,3β,23-trihydroxyurs-12,19-dien-28-oic acid 28-O-β-D-glucopyranosyl ester (R11) , 2α,3β,23-trihydroxyurs-12,19(29) -dien-28-oic acid 28-O-β-D-glucopyranosyl ester (R12) , 2α,3α,19α-trihydroxyurs-12-en-28-oic acid 28-O-β-D-glucopyranosyl ester (R13) , 2α,3β,19α-trihydroxyurs-12-en-28-oic acid 28-O-β-D-glucopyranosyl ester (R14) , 3-O-α-L-arabinopyranosyl-19a-hydroxyurs-12-en-28-oic acid 28-O-β-D-glucopyranosyl ester (R15) , 2α,3α,19α,23-tetrahydroxyurs-12-en-28-oic acid 28-O-β-D-glucopyranosyl ester (R16) , 2α,3β,19α,23-tetrahydroxyurs-12-en-28-oic acid 28-O-β-D-glucopyranosyl ester (R17) , 2α,3β,19α,24-tetrahydroxyurs-12-en-28-oic acid 28-O-β-D-glucopyranosyl ester (R18) , 3β,19α,23-trihydroxyurs-12-en-28-oic acid 28-O-β-D-glucopyranosyl ester (R19) , 2α,3α,19α-trihydroxyurs-12-en-23-formyl-28-oic acid 28-O-β-D-glucopyranosyl ester (R20) , 2α,3β,19α-trihydroxyurs-12-en-23-formyl-28-oic acid 28-O-β-D-glucopyranosyl ester (R21) , 2α,3β,19α-trihydroxyurs-12-en-23,28-dioic acid 28-O-β-D-glucopyranosyl ester (R22) , 2α,3β,19α-trihydroxyurs-12-en-24,28-dioic acid 28-O-β-D-glucopyranosyl ester (R23) , Among them, 1-4 and 6-9 were new compounds. |
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