Font Size: a A A

The Effect Of Chinese Medicine Additive On AES/6501 System Property

Posted on:2010-06-15Degree:MasterType:Thesis
Country:ChinaCandidate:B Z CuiFull Text:PDF
GTID:2131330332476858Subject:Medicinal chemistry
Abstract/Summary:PDF Full Text Request
The paper includes three parts.In the first part, a brief introduction of several properties is present. A review concerning the surface active agent mixed system's research conditions and the traditional function of Chinese medicine in cosmetics are present. The paper identified its topic selection on the basis of this review. Surfactants of the AES and 6501 were used in bath as the object of study. By studying the effect of additive amount on the mixed system of AES/6501, the additive amount of Chinese medicine was found to make the system of AES/6501 mixed in best property.In the second part, according to the experimental results, Sophora was screened out from eight kinds of traditional Chinese medicine which contains antibacterial, anti-inflammatory ingredients richly, and the extraction and separation processes of matrine were investigated.The optimum extraction craft was determined for take 60% ethyl alcohol as the extractant, the ratio of raw solvent to material was 1:8, extracting 2.5 hours at 75℃for three times. Under this technological conditions, matrine's content was 6.5mg/g.732 cation exchange resin was selected to carry on the purification of matrine. The purification craft was:dissoluted and filtrated with 0.5% hydrochloric acid, alkalized with pH10 ammonia, eluted with 75% ethyl alcohol and three times of column volume, collection eluent, dry. After the purification, the purity of matrine could be upto 80%.It was found that in the three part, when AES and 6501 was mixed in different proportion, the AES/6501 system's surface tension and conductivity were situated between two independent surface active agents. After complex formulation, the viscosity was lower than the independent surface active agent. The AES/6501 system's foamability surpassed two sole components, the foam stability was situated between AES and 6501. According to the surface activity of system, the best molar ratio of AES/6501 system was 1:5; The CMC of mixed system was increased by D-Panthenol, and the CMC values of mixed system was not affected when D-Panthenol concentration changed. But itsγCMC was smaller than the blank mixed system system's, when the concentration of D-Panthenol was increased to 0.6%,γCMC reduced to the smallest. Generally speaking, when the concentration of D-Panthenol was under the ranger from 0 to 1.0%, the CMC and ycmc of AES/6501 system would be affected. When the concentration of matrine under the ranger from 0 to 1.0%, CMC of mixed system was not increased with the additions of matrine, the addition of matrine would increase the CMC of complex system and reduceγCMC.When the addition amount of Acer Truncatum Bunge Flavone was 0.2%,0.6%,0.8%, the influence of AES/6501 system's CMC was small. When the addition amount of Alpha Hydroxy Acid was 0.4%,1.0%, the influence of AES/6501 system's CMC was small, but the influence ofγCMC was big. The coductivity of mixed system was increased by four kind of additive in degree, because ion concentration was increased in the solution by the addition of additive. Mixed system's viscosity was smaller than the independent component, only Alpha Hydroxy Acid could effect AES/6501 system's viscosity, the viscosity was related with microstructure, and its mechanism would wait for further studies.AES and 6501 had cooperative effect on bubbles and foam stability, four kinds of additives could enhance the bubbles and foam stability. Also four kinds of traditional chinese medicines additives had certain influence on system's dynamic surface tension, but R1/2 fluctuated throughout in the small scope.lt was explained that the system's dynamic surface activity was not more influenced by four kind of traditional Chinese medicines additives.
Keywords/Search Tags:traditional Chinese medicine, surfactant property, AES/6501 system
PDF Full Text Request
Related items