The Clinic Curative Study Of Prevention And Cure The Cough Variant Asthma With Cold Syndrome Due To The Deficiency By The TheraPy Of Combination Of TCM And Western Medicine

At the attack period, we applied San'ao'erchen decoction and aminophylline to treat 60 patients of Cough Variant Asthma (CVA) (treatment group), contrasted with aminophylline (control group), who diagnosed by Traditional Chinese Medicine (TCM) was cold syndrome due to the deficiency. At remission period, we applied Yupingfeng powder to treat the patients (treatment group), contrasted with ketotifen (control group). At the same time, we were observing what role the atopy was playing in the CVA' s curative effect. Then, look for some theoretic evidences for prevention and cure of the CVA with syndrome of cold due to the deficiency by the therapy of combination of TCM and the western medicine. The results were:(1)There was a remarkable difference between the atopic group and non-atopic group in peripheral blood eosinophil cells ( PBEC ) (P<0.05). (2)At the attack period, as to the disease curative effect, there was no statisticallydifference between the total effective rates of the treatment group and the controlgroup(P>0.05).(3) At the attack period, as to the syndrome curative effect, the total symptomseffective rate of the treatment group (96.67%) was higher than that of the controlgroup (76.67%) apparently (P<0.05). Compared with the control, the treatmentgroup has a better curative effect on the symptoms of nasal obstruction, pallor andpale tongue.(4)At the attack period , the the percentage of peak expiratory flow rate (PEFR%)in tow groups was significantly higher than before being treated. But in effectiverate there had no difference between the two groups (P>0.05).(5)At the remission period, as to the future curative effect, the total effective rate ofthe treatment group(90%) was higher than that of the control group (50%)apparently (P<0.05). The incidence of the syndromes of idrosis and being apt totake a chill in the treatment group was statistically higher than those in the controlgroup.(6) At the remission Period, the PBEC values in patients from treatment group orcontrol group decreased markedly. In two groups, the PEFR% remained at 80%above the intended value with being treated. But the PEFR% in the intended intreatment group was significantly lower than in control group without beingtreated.(7)In three months following-up, the incidence of recurrent cough in the treatmentgroup of the remission period was statistically higher than those in the controlgroup. And the incidence of recurrent cough in atopic group was statisticallyhigher than that in non-atopic group.Conclusions: Atopy plays an important role in the raise of PBEC values and is asignificant risk factor for CVA' s recrudescence. At the attack period, as to thedisease and the immediate curative effect, there was no statistically differencebetween the total effective rates of the treatment group and the control group(P>0.05), and the PEFR% in tow groups was significantly higher than before beingtreated. At the remission period, the incidence of the syndromes, PEFR%, PBECand recrudescence in the treatment group was statistically higher than that in thecontrol group.