The Study Of Changes Of Serum Neuron-Specific Enolase And S-100 Protein In Children With Viral Encephalitis

Objective In order to investigate the changes of serum Neuron-specific enclose and S-100 protein in children with viral encephalitis and its clinical value.Subject The study population included 21 children with viral encephalitis from the department of pedieatrics in the Affiliated Hospital of Medical College Qingdao Univer-sitiy and The City Children' Hospital, The normal control group was 35 healthy children without infectious diseases and derined from never diseases. The ratio of sex and age between the study group and normal group was no different.Methods The serum Neuron-specific enclose was measured by immunoradiossays (IRMA); the serum S-100 protein was measured by enzyme linked immunosorbent (ELISA) tests. The data of serum concentrations of NSE and S-100 protein were expressed as mediant standard deviation. Comparisons between two group were used by student's test. Correlation were determinded by linear regression analysis.Resurts The serum concentrations of NSE were significantly higher in children with viral encephalitis than the normal controls (i' = 5. 9428, P<0. 01); The serum concentrations of S-100 protein were higher in children with viral encephalitis than the normal controls (t' = 2. 8683, P