Research On Effect Of Ulcerative Colitis Treatead By Xiang Lian Wan And Its Compatible Characteristics

Xiang Lian Wan (XLW)is a classical and efficient formula specified for diarrhoea and dysentery.It was first presented in Bing Bu Shou Ji Fang, simply composed of Huanglian and Muxiang.It has the effects of clearing away heatness and relieving dampness.regularing qi and stoping pain.It is used for dysentery .especially for the heat dysentery whose symptoms includes internal heatness, excess thirsty.emptying stool fixing blood and pus.all day and night,anus burning,nonstop diarrhoea and so on.Author makes the deep probation of its disease cause and deduction .character of formular compositon and the later developing and applying. Author think this formula has a precise construction,has a small number of the ingredients but a big effect. Its character is fixing hot and spreading medicine on the basic of using the bitter and cold to drying dampness so that the warm and the cold can restrict each otherjwi and yang can aid each other, depend on each other. Nowdays it has been the one of the common popular formula recipes treating diarrhoea and dysentery .It is the first time to use Muxiang in the dysentery formulas and develop the new thought way treating dysentery for us. Ulcerative colitis(UC) is a cause-unkown inflammatory intestinal disease, its'main clinical symptoms are abdominal pain,diarrhoea,urgent but difficult defecating.stool accompanying pus, juice and blood and so on,defmed to the diarrhoea and dysentery in the TCM. According to the cognition that the modern medicine has about the ulcerative colitis and using the modern pharmacology researching methods, author makes an analyse of the formula and probe its compositive principle and entity by making upmodels on the mice of ulcerative colitis caused byDextron Sulphate Sodium(DSS).The result indicates that XLW has a good effect on anti-inflammation, abirritation and lowering the blood serum IL-6 level so proves that the formula's compositon is of rationality and science. Lowering the disease activity information (DAI) degrading,improving symptoms and the colon pathologic changes of the colon . So author's dissertation provides experimental evidences for the clinical application.