Clinical Observation On Treating Coronary Atherosclerotic Heart Disease By Guan Tong Soup

At the beginning of the 20^th century, Coronary Heart Disease (CHD) was the leading cause of disable and death in the United States. With the progress of medical and health work, the morbidity and mortality of CHD trends toward descending in western country. But it is still a fact that one person should be dead from cardiovascular disease per 33 seconds, which was reported by American Heart Association. With the raise of life level and aging of population, the morbidity and mortality of CHD is trending toward ascending in China now. Except that, many risk factors of CHD, such as hypertension, hyperlipemia, big BMI,DM and emotional stress are all in ascending trend. We can indicate that CHD will threaten the health of more people in the future.The incidence of CHD in our country will increase considerably in the next ten to twenty years though it is lower than that in the western countries. So the measurement of interference,education and therapeutic of CHD shoud be strengthen. And so exploring effective methods for preventing and treating CHD is the key problem in the medical field.CHD angina pectoris(AP) is owing to epigastic pain and cardiac obstruction in Traditional Chinese Medicine(TCM). In theory of TCM, deficiency qi and blood stagnation in collateral of heart is the key mechanism. If blood stagnationin collateral,vessels will be obstructed. So blood can not nourish the heart, AP is formed. From the view, therapeutic principle of AP should be made to get rid of blood stagnation. Through quickening the blood and transforming stagnation and freeing vessels, collaterals can be dredged, and the symptom of AP can be pacified. Furthermore, it can also modulates the release of activate factors in less the pathology deteriorates.To treat CHD effectively is the focus. With the progress of mechanic researches, therapeutics of CHD has become more and more mature. It had developed a systematic therapeutic method in the treatment of CHD during several thousands of years and showedsuperiority for its characteristics of therapy with syndrome differentiation, treatment based on the principle cause and integration of man and nature.Guan tong soup is an effective prescription in the treatment of cardiac obstruction of deficiency qi and blood stagnation type according to our experiences. 100 cases were randomly divided into two groups, that is treatment group and control group which is given TongXinLuo capsule administration. It showed that GuanTong soup had good regulations on breaking times of angina pectoris, expending capacity of Nitroglycerin, clinical syndrome of patients, electrocardiogram and metabolic disorder of lipid and is superior to TongXinLuo capsule.