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Experimental Research Of The Effect And Mechanism Of Dengzhanhua Against Myocardial Ischemia Of Canines

Posted on:2007-04-03Degree:MasterType:Thesis
Country:ChinaCandidate:Z Y JiaoFull Text:PDF
GTID:2144360212459417Subject:Pharmacology
Abstract/Summary:PDF Full Text Request
Incidence of ischemic heart disease (IHD) is very high. IHD is the third killer among all the diseases. It is especially commonly seen in European-American countries. In our country, its incidence is gradually rising, so severely threatening people's health and lives. So it is of great importance to improve the prophylaxis and treatment of IHD.There are many tradional Chinese medicines used to treat IHD. But some of them have many toxic effects and can not decrease the fatality, so new drugs that treat IHD are expected. Dengzhanhua is a herbaceous plant, It is a widely spread galenical in YUNNAN civil. It is perennial duantingfeipeng dry quancao.To investigate its effect and mechanism on the experimental acute myocardial ischemia, the acute myocardial ischemia model was established by ligating the left-decendent coronary artery in canines. The square measure of infarction heart muscle, the ischemia degree and score, the content of serum enzymes,...
Keywords/Search Tags:Dengzhanhua, myocardial ischemia, AST, CK, LDH, free radicals hemodynamics, trace element
PDF Full Text Request
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