The Experimental Study Of The Theory Of Meridian Tropism About Pilose Asiabell Root And Astragalus Root Based On NEI Network

Objective: To discuss the theory of meridian tropism based on NEI network, we observe Pilose asiabell root and Astragalus root which enter the spleen meridian, gastrodia tuber which dosen't enter the spleen meridian whether have different influences on substance P content in brain-gut axis. Methods: We use experimental spleen-deficiency rat model and observe the effects of three kinds of herbs on the D-xylose content of serum, the ATPase and LDH activity of muscle, substance P changes in brain-gut axis. And then we process these datas with stepwise regression analysis to study the relativity between regulation of brain-gut axis and attribution to the spleen meridian. Result: Pilose asiabell root and Astragalus root have better effects than Gastrodia tuber on the indexes of D-xylose content of serum, the ATPase and LDH activity of muscle. Pilose asiabell root, Astragalus root and Gastrodia tuber have different effects in the experiments of substance P changes in brain-gut axis and in the correlation analysis. Astragalus root has a better correlation than Pilose asiabell root and Gastrodia tuber in the stepwise regression analysis. Conclusion: We presume that the attribution to the spleen meridian is correlated with the regulation of brain-gut axis. It is feasible method that we use the multiple correlation analysis to research the theory of meridian tropism based on the NEI network.