Observe Distribution Of Arteriostenosis In Patients With Ischemic Cerebral Vascular Disease By DSA And Analyze Risk Factors

Objective:Observing Distribution of intracranial and extra cranial Arteriostenosis in Patients with Ischemic Cerebral Vascular Disease(ICVD) by DSA,analyze relationship between the distribution of 1 arteriostenosis and the risk factors of ICVD,provide reference for preventing and treating ICVD.Methods396 patients of ICVD detected by DSA were detached three groups. as follows:Ⅰgroup, pure intra cranial artery stenosis;Ⅱgroup, pure extra cranial artery stenosisⅢgroup, intra and extra cranial artery stenosis.Meanwhile,establish one group which were negative. We measured biochemical indicators such as TG, TC, HDL, LDL, Apo A, Apo B, CRP, FIB and so on., And collected these risk factors with self-design questionnaire such as sex, age, long-term smoking, long-term drinking, hypertension,etc of all patients.The risk factors were analyzed by One-Way ANOVA and Binary Logistic Regression Analysis.Research ResultsPure extra cranial artery stenosis occupied the great majority of these three groups (P<0.01).The majority of sigle artery stenosis were bigger than that of two or more artery stenosis (P＜0.01). The positions of lesion were mostly in extra cranial artery.These lesions mostly were sinus of ICA and the beginning of VA,moreover,the lesions of intra cranial artery mostly were MCA(M1).395 lesions in 276 patients of CI were mostly the first grade (41.77%);44 lesions in 37 patients of TIA were mostly the third grade(38.64%);while,73 lesions in 83 patients of VBI were mostly the first grade(45.21%). One-Way ANOVA and Binary Logistic Regression Analysis prompted: The risk of intra cranial or extra cranial artery stenosis will enlargeWhen growing (OR=1.046);the male are more liably to fall ICVD(P<0.05),severe extra cranial artery stenosis occupied the great proportion long-term smoker(37.3%),while intra cranial artery stenosis occupied the great proportion long-term drinker(50.7%).In patients of DM,they were mostly intra cranial artery stenosises(35.3%),while extra cranial artery stenosis or middle/severe intra and extra cranial artery stenosises in patients of HBP(77.1%).The descending of ApoA (OR=0.001),the ascending of TG(OR=1.034),LDL(OR=1.068),ApoB(OR=2.522) will enlarge the risk of cerebral artery stenosis.Conclusion:1 Single artery stenosis and pure extra cranial artery stenosis occupied the great majority of these three groups such as group of CI, group of TIA and group of VBI.2 Single artery stenosises of extra cranial artery stenosis are mostly in sinus of ICA and the beginning of VA,while the lesions of intra cranial artery mostly are MCA(M1).3 The first grade artery stenosis occupies the greatest proportion of these three groups(41.77%), which indicates that closely relationship is being between the first grade artery stenosis and ICVD.4 Age,different nature,HBP,DM,long-term smoking,long-term drinking,descending of ApoA and ery stenosis.ascending of TG,LDL,or ApoB are the risk factors of artery stenosis. Patients of advanced age,male,HBP, long-term smoking are liably fall extra cranial artery stenosis,while those of DM,long-term drinking,descending of ApoA ascending of ApoB are liably to fall intra cranial artery stenosis.