| Objective:To observe the clinical efficacy of LuFengFang (LFF)decoction in treating verruca plana(VP),to evaluate objectively the Serum level of IL-2, IL-4 andγ-IFN in patients and to assess the effect of LFF decoctilon on immunity function. Methods:70 cases with VP recruited was divided into two groups randomly, LFF decoction group, as compared with ZhuanYiYinZi(ZYYZ) capsule group, and in the same time, give the traditional chinese medicine to two groups with external use,8 weeks as a course. After the treatment, observe the clinical efficacy of LFF decoction and ZYYZ capsule. Besides,. Serum levels of IL-2,IL-4 andγ-IFN in all patients were observed and compared before and after trentment. Results:After the trentment,at the clinical efficacy, comparision between the two groups showed significant difference. And the LFF decoction group is better than the ZYYZ capsule group.And at the same time,Serum level of IL-2 and y-IFN in the patients of two groups were higher than that before trentment,as the Serum level of IL-4 was lower than that before trentment. But comparision between the two groups showed insignificant difference. Conclusion:LFF decoction has reliable efficacy in treating VP, low recurrence rate and side effect on. The mechanism of the therapy of LFF decoction may be credited with the anti-virus and improving immunity action.
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