Chinese Medical Diagnosis And Treatment For Asthmatic Infants Aged One To Five Years In Remission Period

Objective:To investigate the diagnosis and treatment of asthmatic children aged 1 to 5 years with positive predictive index in remission period. To reduce the frequency of asthma attack by intervention therapy and evaluate the outcome with qualified index.Methods:Eighty patients were randomly divided into control group (auto-moxibustion, n=20) and treatment group (auto-moxibustion plus TCM Peiyuanshengjing Soup-oral taken, and/or TCM injected via Foot Three Li, groupⅠ-Ⅲ). Staged therapy was performed based on pathogenetic conditions of patients. The scores of deficiency syndrome of lung, kidney and spleen, ratio of eosinophil (EO), frequency of asthma attack, daytime and nocturnal symptom scores and frequency of drug administration were evaluated 3,6 and 9 months after treatment.Results:①Statistical difference was detected between the scores of deficiency syndrome of lung, kidney and spleen at 3,6 and 9 months after treatment (P< 0.001), indicating all these treatments were effective to reduce the syndromes scores, especially groupⅢ.②Sharpe decrease of EO ratio was observed in all groups, however, statistical difference was only detected 6 months after treatment (P=0.003). For EO ratio, significant differences were detected after fixing treatment factors in each group (P<0.001). demonstrating time was the only factor for EO ratio change.③For the frequency of asthma attack, no statistical difference was detected 3 months after treatment (P=0.895). Six months after treatment, statistical differences were detected between treatment group and control group (P=0.002). Statistical differences were observed in treatment group and control group 9 months after treatment (P<0.001), however, no difference was detected between groupⅠand groupⅡ. In addition. the frequency of asthma attack showed remarkable difference in each group after fixing treatment factors, indicating each treatment was effective for reducing frequencies of asthma attack, especially groupⅢ.④The duration for daytime and nocturnal symptom showed remarkable decrease in each group at 3.6 and 9 months after treatment (P<0.001). For daytime symptoms, statistical difference was detected in each group after fixing treatment factors, indicating each treatment was effective for reducing the duration of daytime symptom.⑤With regards to administration frequency of release drug. no statistical difference was detected 3 months after treatment (P= 0.758). Significant difference were detected between treatment group and control group 6 months after treatment (P=0.001). however, no difference was detected between treatment group. Significant difference were detected between treatment group and control 9 months after treatment (P< 0.001), however, no significant difference was observed between groupⅠand groupⅡ. After fixing treatment factors, significant differences were detected in each group at the terms of administration frequency of release drug, indicating intervention therapy (≥3 months) was necessary to reduce drug administration and bring the disease under control. Three months after treatment, the dose of release drug showed remarkable decrease in each group, especially groupⅢ.⑥With regards to disease control, significant difference was observed in each group (P=0.001), especially groupⅢ. The total effective rate also showed significant statistical difference in each group (P=0.018).Conclusions:Intervention therapy based on Chinese medical diagnosis and treatment was efficient to decrease the scores of deficiency syndrome of lung, kidney and spleen of infants with positive asthma predictive index, reduce the frequency of attack, and control the conditions.