| Due to the development and application of theory and technology in the field of molecule and cell biology, the research of exercise and immunology is going deeper. The discovery of interleukin in recent years has led to a groundbreaking progress in people's understanding of the functions of immune system. In some areas people have been able to understand its working on the level of molecule. This study tries to observe the responsive and recovery characteristics of immune function of IL induced by eternally aerobic exercise.This research object is SD rats, which have been divided into four groups : 1. Control (WK-R) 2. rats killed before exercise (WK-B) 3. rats killed immediately after exercise (WK-A) 4. rats killed 3 hours after exercise (WK-3h).The rats were randomly divided into 19 groups in all according to the length of time used for exercise: 1. zero week (WKO) 2. one week (WK1) 3. two weeks (WK2) 4. three weeks (WK3) 5. four weeks (WK4). We observe the experimental study about effects on interleukin (IL-1^ IL-2> IL-6)of rats after eternally aerobic exercise and try to provide experimental evidence for the effect of exercise on the immune system . The results are as follows:1. The activity of serum IL-1 of WKO-A is significantly higher than that of WKO-R(P<0.01) and after 3 hours' rest, the activity of serum IL-1 of WKO-3h is significantly lower than that of WKO-A(P<0.05),but it is still significantly higher than that of WKO-R(P< 0.01) .The curves show a tendency of rising at first and going down later. During the four weeks of eternally aerobic exercise, all groups except WK3-3H show a tendency of rise-rise-dropping ". The rising of WK3 and WK4 is more obvious. It shows that adequate aerobic exercise can effectively activate immune system, increase IL-1 secretion which is the medium between immune cells and prolong the rise in the IL-1 level. It suggests certain relevance between the strengthening of the immune system and the rise of serum IL-1 level.2. The activity of serum IL-2 of WKO-A is lower than that of WKO-R, and after 3 hours' rest the activity of serum IL-2 about WKO-3h is higher than that of WKO-A. However, it is still lower than that of WKO-R. The curves show a tendency of lowering down at first and rising later with no significant change (P>0.05). The result of WKO and WK1 are very similar to the above-mentioned tendency, but they have experienced greater change. The changes occurred in WK3 and WK4 are not noticeable, and can be illustrated by a straight line. It shows that serum IL-2 is comparatively stable and has not been affected by the aerobic exercise. The improvement of immune system motivated by aerobic exercise is the result of a long-term accumulation, and it is also related to the proper stimulating intensity.3. The activity of serum IL-6 of WKO-A is significantly higher than that of WKO-R, the activity of serum IL-6 of WKO-3h is still higher than that of WKO-A and WKO-R, but with no significant change(P>0.05). The curves show a tendencyof sharp rising. WKO and WK1 are similar in the changes of their IL-6, but the change of WK1 is greater. IL-6 level shows a noticeable decline in WK2. It shows no obvious changes in WK3 and WK4, which might be the result of the rats' accommodation to the aerobic exercise. The result shows that IL-6 responds to aerobic exercise with a rise and manifests a tendency of continuing rise after 3 hours. Nonetheless, whether the influence of aerobic exercise on the immunity of body is linked with the serum IL-6 level or not needs long-term observation and tests.4. In the tendency of change in the serum interleukin (WK-R) during the four weeks, the changes in IL-1 are as follows: There is no significant change among WK1 and WK2 .WKO (P>0.05). The activity of serum IL-1 of WK3-all and WK4-all is significantly higher than that of WKO-R except WK4-R and WK4- (P<0.01) .But there is no significant change in IL-2 and IL-6 ever since the first week(P>0.05). We believe that on the one hand , as time goes by, the age of rats has in...
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