Retrospective Clinical Study On The Treatment Of Heat-induced Gastric Ulcer Disease

Purpose: Learning with Zhou Xuewen old professor clinical experience prescription "heat clearing and detoxifying, eliminating carbuncle and growing muscle" toxic heat stagnating in gastric ulcer treatment, observe the effect on the patients clinical symptoms, signs, area of ulcer and gastroscope performance, found the clinical evidence for TCM clinical treatment of heat toxin accumulation in the stomach type gastric ulcer.Material and method: Choose from June 2011 to 2012 October time period came to the Department of Gastroenterology; the First Affiliated Hospital of Liaoning University of traditional Chinese medicine meet the inclusion criteria of 98 patients, for the 98 cases of patients by random grouping method will be 98 cases of patients were randomly divided into treatment group and control group. in which the number of the control group 46 cases, 52 cases of treatment group. Given to the patients in the control group meal before fasting oral capsule of omeprazole, 20 mg, daily morning and evening meals fasting oral each time, amoxicillin 1.0 g, twice a day, oral, clarithromycin dispersible tablets 0.5g, 2 times a day, 30 days for a full course of treatment; patients in the treatment group drugs used in patients in the control group used drugs based on the service old professor Zhou Queen experience decoction treatment should be, "heat-clearing and detoxifying, eliminating carbuncle and growing muscle" treatment with Decoction, pharmaceutical compositions for: Huanglian6 g Kushen6g Yejuhua10 g Pugongying10g Wuzeigu10 g Zhebeimu10g Baiji10 g Huangqi15g, the decoction, one dose a day, divided into early before dinner twice fasting oral and overall course of treatment of 4 weeks. Will all cases before and after treatment were collected and recorded the information of TCM four diagnostic methods, before and after treatment over 4 weeks underwent gastroscope, and record the inspection results. All the data obtained by using SPSS18.0 statistical software for statistical analysis.Results:1. Treatment 1. 4 weeks later, on the therapeutic effect of TCM syndrome, treatment group, the clinical symptoms of the patients recovered number 14 cases, effective number for 19 cases, effective number for 13 cases, invalid number of 6 cases, the total clinical efficiency was 88.46% in the control group, the clinical symptoms of the patients were cured number in 7 cases, markedly effective number 12 cases, effective number for 18 cases, invalid number of 9 cases, the overall clinical efficiency was 80.43%. In the treatment group, the clinical overall have rate was significantly higher than that in control group, compared the difference of two groups had significant difference(P < 0.05).2. The patient underwent gastroscope comparing therapeutic effect, the treatment group cured 13 cases, markedly effective in 18 cases, effective in 15 cases, invalid in 6 cases, the overall effective rate was 88.46%, in the control group, the clinical cure in 8 cases, markedly effective in 10 cases, effective in 18 cases, invalid 10 cases, the total efficiency was 78.26%. The treatment group overall efficiency are significantly higher than that of the overall efficiency of the control group, the difference between the two groups of data compared with statistical significance(P < 0.05).Conclusion: Treatment group in improving the heat toxin accumulation in the gastric ulcer in patients with clinical symptoms, relieve epigastric pain and promote ulcer healing were superior to the control group, Professor Zhou Xuewen using "heat-clearing and detoxifying, eliminating carbuncle and growing muscle" of traditional Chinese philosophy, traditional Chinese medicine surgery "disappear, hold in the palm, fill" treatment directly introduces in the clinical treatment of toxic heat stagnating in gastric ulcer, obtain good effect, worthy of future Department of Gastroenterology in the treatment of such diseases in further research and clinical application.