On basis of the science of epidemic febrile disease, combining with the achievement of Western Medicine, and resorting to modern technology, we probed the pathogencsis and developing rules of noxious heat and blood stasis syndrome ,and we discussed the mechanism and application of Nourishing Yin and Producing Fluid thoroughly. In this article we expounded that the treatment of Nourishing Yin and Producing Fluid is an important therapeutic principle, its establishment is based on pathology of excess noxious heat, and Yin and collateral impairment Fire and heat are primary factors in the occurrence of noxious heat and blood stasis syndrome. Noxious heat, Yin and collateral impairment are its basis, and weakened resistance and collapse are its an impoitant developing trend eney .The mechanisms of nourishing Yin and producing fluid are as following: which can eliminate the pathogens; nourishing Yin, protecting collaterals and promoting blood circulation which can reduce the impairment; reinforcing Yin and resistance which can avoid collapse. The basic principles treatment catching on adaptive symptoms, paying attention to herb combination and applying gist of medicament In additions, a new animal model that suffered from noxious heat and blood stasis syndrome was established, and the mecbamism of nourishing Yin and producing fluid was studied. The results showed this treatment method could enhance the ability of antioxidation, resiste the damnifies of LPS and free radical on cell, adjust the secretion of the vascular endotheium cells, modulate the mechanism of coagulation improve hemorrhcology , enhance the immunity of the body, maintain the stabili7ntion of liquid and electrolyte metabolize. |