Puerarin Injection Treatment Of Unstable Angina Clinical Efficacy Observed

ObjectiveTo observe the clinical efficacy of Puerarin-injection in treating patients with unstable angina (UA) through comparison with compound injection of red sage root, and explore the mechanism and offer the scientific basis for the further clinic application.Methods1. Clinical data: A total of 86 patients were randomly divided into two groups: Puerarin grounp (43 cases) and control group (43 cases). All of the patients' clinical symptoms conform to the diagnosis standard of unstable angina pectoris and at the same time, conform to the pattern of stagnation of the heart blood.2. the medicinal usage: The patients in treatment group were cured with puerarin-injection 8ml iv drip which were mixed with 5% glucose solution 250ml each time , qd and control group compound injection of red sage root 16ml iv drip which were mixed with 5% glucose solution 250ml each time ,qd. One period of treatment was 14 days . During the course, all patients were permitted to the use of nitroglycerin, aspirin, ACEI and Beta-Adrenergic Antagonists, others can that would have an effect on the result were forbidden, including other drugs for treating angina pectors, fat food, acridity food, smoking and drinking.3. The curative effective and safety observation and test: For all the patients,general conditions, angina pectoris sympotoms, ECG, sympotoms and signs were all observed. In addition, blood route, urine route, stool route, liver kidney function, blood rheology and hemorheology were tested before and after the treatment.4. The Stat. method: The data was analyzed after observation. The count materials, the measuring materials and the grade materials were examined with X2,T-test and Ridit respectively.Result1. The clinical curative effective of angina pectoris sympotoms: The treatment group: obvious effective rate 53. 50%, progressive rate 41. 90%, total effective rate 95.30%. The control ground : obvious effective rate 34.90% , progressive rate 34. 90% , total effective rate 69. 80%. The effect of the treatment group was better than that of the control grounp (P< 0. 01) .2. Electrocardiogram: The treatment group: obvious effective rate 44.19%, progressive rate 32. 56%, total effective rate 76. 74%. The control ground : obvious effective rate 18.60% , progressive rate 34.88% , total effective rate 53. 49%. The effect of the treatment group was better than that of the control group (P < 0. 05 ) .