Correlation Study Of Six-minute Walk Test With Lung Function And Quality Of Life In Patients With Moderate-sever Chronic Obstructive Pulminary Disease.

Objective:1.Discussing the relationship of six minute walk test with quality of life in patients with chronic obstructive pulminary disease to explore more simple evaluation indexes of quality of life.2.Discussing the relationship of six minute walk test with lung function in patients with chronic obstructive pulminary disease to explore more stiutable method of lung function in basic-level medical sysrem.Methods:1.The method of patients selected was used by Cluster sampling. 40 patients with stable chronic obstructive Pulmonary disease(COPD) were selected from the Department of the first one Hospital of Dalian Medical University between August 2009 and December 2010. Diagnostic criteria is the diagnosis and treatment of chronic obstructive pulmonary disease guidelines (2007) revision. Finishing the lung function, SGRQ and six minute walk test in the same day.2.The inspection of lung function was completed by one doctor. Patients were graded according the FVC%, FEV₁% and FEV₁/FVC.3.St George,s respiratory questionnaire. Every subject conduct SGRQ score separately without any prompting after lung function test and giving explanations by professionals for the no undrestanding part. SGRQ is composed of the respiratory symptoms section, the activity section and the impacts section.Calculated by the special software get total score and there section scores. The range of score is 0-100, the higher the score representing the worse the quality of life. 4.Six minutes walk test.Conducting in a quiet interior corridors, length of 15m, and gudianced by proffessional. The Borg score were collected before lung function test to clere the situation of dyspnea in rest state. The subjiects can adjust their speed according to their situation. The Borg score were collected once more after test to clere the situation of dyspnea in exercise state.5.SPSS11.5 software was used for statistic analysis. Normal distribution resources were represented x±s. Pearson Correlation analysis were used for analyzing realthionship of 6MWT and SGRQ, lung function. P<0.05 for differences are significant.Results:1.SGRQ total score and three part are consistent with normal distribution. SGRQ total score is(35.47±19.70), symptoms section score is (40.27±22.91), the activity section score is (49.52±20.20), the impacts section score is (27.74±21.93), activity section score is the highest.Pearson correlation analysis shows the correlations between SGRQ total score and three-part score are significant,which represented a good consistency in evaluation on symptoms, activities, psychological status of patients using SGRQ and the quality of life of Patients.2.Lung function testing results: FEV1 / FVC (45.69 + 7.18), FEV1 % (38.95 + 11.7), FVC % (63.41 + 13.62).3.Six minutes walking distance is (425.92±100)m.4.Pearson correlation analysis shows the correlation between six minutes walking distance and activity section score is significant(r=-0.443, P=0.006), and has no correlations with other section scores. SGRQ total score has correlation with FEV1/ FVC(r=-0.323, P=0.045).Conclusions:1.Six minutes walking can evaluate the activity limition in patients with stable chronic obstructive Pulmonary disease, which can be used as objective evaluation indexes of exercise endurance, in clinical practice.2.6 minutes walk test cannot replace conventional lung function test, but can be used as one effective supplementary of lung function test.