Chinese Herbal Compound In The Treatment Of Coronary Heart Disease And Angina Pectoris System Evaluation

Objective:Angina pectoris of coronary heart disease cardiovascular disease is the common disease,frequently-occurring in. With the economic and social progress,people life style changes,angina pectoris of coronary heart disease incidence rate is more and more high.Although western medicine treatment of angina pectoris of coronary heart disease by means of rapid development,but there are side effects of drugs,after interventional therapy of coronary restenosis,and expensive medical cost and other issues.At present,with Chinese medicine treatment of angina pectoris of coronary heart disease,become our country medicine research in the areas of focus.The subject of the use of evidence-based medicine approach to the evaluation of Chinese herbal recipe in treating coronary heart disease angina pectoris.Methods:According to the international Cochrane network system evalution method,computer retrieval of OVID platform Cochrane library controlled clinical trials database(CCTR),the United States Medical Abstracts(Medline),China Journal Full-text Database(CNKI),VIP Chinese science and Technology Periodocal Full-text Database(VIP),Chinese biomedical literature database(CBM)and Wanfang database,and manual supplement search.Collection of Chinese herbal compound in the treatment of angina pectoris of coronary heart disease a randomized controlled trial.On the incorporation of research methodology for quality evaluation,using the Cochrane collaboration with Revman4.2software system analysis.Results:Eventually enrolled in13randomized controlled trials,are Chinese,methodological quality assessment are class C.Meta-analysis showed:Chinese herbal compound in improving the symptoms of angina,12of the Meta-analysis showed that Chinese herbal compound is superior conventional western medicine or(and) Di-ao-xin-xue-kang capsule [RR=1.28,95%CI(1.21,1.36), P<0.00001], with statistical significance.The improvement of electrocardiogram,12of the Meta-analysis showed that Chinese herbal compound is superior conventional western medicine or(and) Di-ao-xin-xue-kang capsule [RR=1.49,95%CI(1.35,1.66), P<0.00001], with statistical significance.In the thaditional Chinese medicine curative effect,2of the Meta-analysis showed that Chinese herbal compound is superior conventional western medicine or(and) Di-ao-xin-xue-kang capsule [RR=1.21,95%CI (1.05,1.39), P=0.007], with statistical significance.In the traditional Chinese medicine curative effect of individual symptoms,2study analysis showed improved chest pain,chest tightness,shortness of breath,yaoxisuanruan, Chinese herbal compound is superior conventional western medicine or(and) Di-ao-xin-xue-kang capsule.Improvement of palpitation,insomnia or little sleep,no significant difference between two groups.Effect of blood fat,5studies of the Meta-analysis shows on triglyceride,cholesterol,high density lipoprotein influence, Chinese herbal compound is superior conventional western medicine or(and) Di-ao-xin-xue-kang capsule;on low density lipoprotein effects,no significant difference between two groups.On blood rheology (including the whole blood viscosity,plasma viscosity,hematocrit)effects,2of the Meta-analysis showed that Chinese herbal compound is superior conventional western medicine or(and) Di-ao-xin-xue-kang capsule.Conclusion:Chinese herbal compound in the treatment of angina pectoris of coronary heart disease with routine western medicine or(and) capsule in treating results has aduantages compared to,can alleviate the symptoms of angina pectoris;improve the electrocardiogram; reducing triglyceride,cholesterol,high density lipoprotein;improvement of blood rheology indexes,for angina pectoris of coronary heart disease patients to provide more effective,reliable treatment options,for clinical provides more choices.But due to the incorporation of small amount of sample, methodological quality on the low side,"funnel plot"suggests the presence of publication biasmay,therefore,for Chinese herbal compound in the treatment of angina pectoris of coronary heart disease provide a strong scientific basis,but also helds the combination of Chinese medicine with their own characteristics,multi-center,large sample,high quality randomized double-blind controlled trial to prove.