Study Of Genetic Polymorphism Of17Y-STR Loci In Hui Population From The Linxia

Objective:To investigate the genetic polymorphisms of17Y chromosomal STRs of the Hui population in the Linxia Hui Autonomous Prefecture and evaluate their forensic application.Methods:The template DNAs were extracted from blood samples of424unrelated Hui population male individuals and seventeen Y chromosomal STRs were amplified using the AmpFlSTR(?) YfilerTM PCR Amplification kit (Applied Biosystems, Carlsbad, CA, USA). Amplified products were separated and detected using the ABI3730x1Genetic Analyzer (Applied Biosystems, Carlsbad, CA, USA). The data were analyzed using GeneMapper ID v3.2(Applied Biosystems, Carlsbad, CA, USA). The exact test of the Hardy-Weinberg equilibrium was performed using ARLEQUIN software version3.11.Admixture was analyzed by ADMIX2.0.Results:there were total361different haplotypes in the424unrelated Linxia Hui males,of which310were unique.The observed haplotypes diversity (HD) value was0.9995. The gene diversity(GD) of the17Y-STRs ranged from0.4713(DYS391)to0.9680(DYS385a/b). The admixture analysis showed that over60%of the Hui population Y chromosomes was derived from the Han in China, Central Asian MRH:0.376873, Mongolian MRH:0.342721Conclusion:The17Y-STR loci in Hui population of Linxia Hui Autonomous Prefecture are highly affluent genetic polymorphic and can offer valuable genetic data for paternity testing and paternal genetic lineages evolution. The improvement of the forensic database to provide basic data.