Sjogren’s Syndrome Type Of Traditional Chinese Medicine Clinical Study Of Correlation Factor

Objective: Through in sjogren’s syndrome（SS）patients with traditional Chinesemedicine syndrome type and related factors for statistical analysis,studying of SS TCMsyndrome type and age,sex,duration,season,TCM syndrome type,laboratory examinationdata,the activity of disease correlation.In order to reveal the distribution regularity of TCMSyndromes, and provide foundations for establishing pattern identification standards of SSin the future.Methods:The subjects were collected with epidemiological observationmethod,retrieved the hospital medical record,filled in the self-designed questionnaire.The87patients who meets the criteria for inclusion with SS carry on the dialecticalanalysis,and classify the syndrome type of Traditional Chinese Medicine in strictaccordance with TCM syndrome classification.This research can be divided into toxic heatand yin deficiency syndrome,dampness-heat blockage syndrome,Qi-Yin deficiencysyndrome,Phlegm-blood stasis syndrome,dry-heat with yin-deficiency syndrome.Construction of full name, sex, age, course of disease, type of TCM,laboratory indexes,theactivity of disease score. Final we can analysis the relationship between them and the typeof TCM.Results:①This study of87patients,Qi-Yin deficiency syndrome accounting for27.59%of all cases;phlegm-blood stasis syndrome accounting for25.29%of allcases;toxic heat and yin deficiency syndrome accounting for19.54%of allcases;dampness-heat blockage syndrome accounting for17.24%of all cases;dry-heat withyin-deficiency syndrome accounting for10.34%of all cases.②Five syndrome in thegender,season distribution,the difference does not have statistical significance (P＞0.05);inthe age distribution,the eldest is eighty and the youngest is twenty,mean49.14±13.35yearsof age, the difference does not have statistical significance (P＞0.05).In the course of the disease distribution,mean50.33±29.89months, the difference was statistically significant(P＜0.05),the average course of Qi-Yin deficiency syndrome is longest, dry-heat withyin-deficiency syndrome is shortest.③Different symptom integral of disease in each typeswere markedly different (p＜0.05),the average symptom integral of toxic heat and yindeficiency syndrome is maximum, dry-heat with yin-deficiency syndrome isminimum.④RF,ESR,CRP,IgG and anti SSB in related types were markedly different(P＜0.05),the average of ESR,CRP and IgG of toxic heat and yin deficiency syndrome ismaximum,and anti SSB positive rate is maximum too.But IgA,IgM,ANA and anti SSAwere not markedly different(p＞0.05).⑤Different disease activity degree of disease ineach types were markedly different (p＜0.05),the highest was toxic heat,Phlegm-bloodstasis syndrome was second.According to the disease activity,if SSDAI≥5wasactivity,and SSDAI＜5was inactivity. Toxic heat and yin deficiency syndrome is themain syndrome with activity disease,and dry-heat with yin-deficiency syndrome is themain syndrome with inactivity disease.Conclusion:①Sjogren’s syndrome is more in women than man.The sex ratio is1:20.75.To45~59years old is more incidence than others.In the course of the diseasedistribution, he average course of Qi-Yin deficiency syndrome is longest, dry-heat withyin-deficiency syndrome is shortest.②There is no clear interrelation between the TCMsyndrome type and seasons.③In87patients with sjogren’s syndrome, the largest number ofcases is Qi-Yin deficiency syndrome.Toxic heat and yin deficiency syndrome,Qi-Yindeficiency syndrome and dry-heat with yin-deficiency syndrome are more serious thanothers.Dry-heat with yin-deficiency syndrome is relatively stable.Phlegm-blood stasissyndrome, which go through the whole progress of the disease.④The TCM syndrome typeand laboratory indexes,SSDAI have some correlation,the average of ESR,CRP, IgG andSSDAI of toxic heat is highest,which can be become the syndrome differentiation standard.