Research On Standardized Magnoliae Officinalis Cortex Standardtechnology And Quality Evaluation

The dried bark of Magnolia officinalis Rehd.et Wils or Magnolia officinalis Magnolia officinalis Rehd.et Wils. Var.biloba Rehd.et Wils, the root bark and branch bark, bitter, acrid, warm, spleen, stomach, lung, and large intestine, have dampness phlegm, lower gas temperature in addition to full effect, mainly used in clinical hysteresis injury, the wrist ruffian vomiting and diarrhea, abdominal distension and diarrhea, cough and phlegm food product gas lag and so on. Pieces of Magnolia officinalis standard and quality monitoring helps manage Magnolia Puerariae market, in order to facilitate sampling and testing, Magnolia Pieces standard exists in the form of powder, stable and consistent quality standards, also known as homogenization Pieces Pieces. This selection of Enshi area Magnolia pieces of the original ingredients as the standard and orthogonal experiment method combined with Magnolia officinalis its medicinal characteristics of its own preferred its grinding process, and ultimately come to apply to most of Magnolia officinalis standard Pieces good grinding process, then the use of modern scientific and technological methods and means of its evaluation of the system, to study its quality evaluation.This paper studied Magnolol pieces of technology and quality evaluation:1. Determine the standard pieces raw medicinal their base source, origin. OK produced in Enshi dry Magnoliaceae Magnolia officinalis bark, root bark and branch bark for the processing of standard pieces raw herbs.2. Determine the uniform standard specification Magnolol Pieces that, according to the physical and chemical properties of the prototype pieces Magnolia officinalis and reference medicinal herbs to determine the optimal granularity of control Magnolol standard Pieces, then take compared by orthogonal good process method, combined with the yield, and the content of magnolol and honokiol composite score, final selection of the best Magnolia pieces grinding process. The results showed that 70% of feeding amount taken, crushed three times in a row, each time 45 s for the best grinding process.3. Pieces of Magnolia officinalis standard optimal grinding process is preferably carried out the study. Using the best technology production batches of standard pieces, their traits were microscopic identification, TLC, relevant inspection(inspection of water, total ash and acid insoluble ash, extract), determination of volatile oil, the active ingredient was measured, the results were in line with 2010 edition of "People’s Republic of China Pharmacopoeia" requirement, and the results are highly consistent description of the preferred process to produce Magnolia pieces powder is very uniform, the optimum is stable and feasible.4. Magnolia optimized standard pieces optimum grinding process to produce three batches of standard pieces for HPLC characteristic spectrum research, and control of medicines and Magnolia characteristic spectrum compared with the results of three batches of powder than the control ingredients Magnolia Bark pieces characteristic pattern two more peaks, and the three batches of Magnolia officinalis pieces powder characteristics highly similar pattern in the number of peaks, peak height and peak time, and peak height ratio of magnolol and honokiol, which proves after using the optimum crushing Magnolol pieces uniform quality standards, technology is stable and feasible, and can be characterized by patterns in the liquid phase and the peak height and peak height ratio of magnolol honokiol magnolol as a standard pieces quality evaluation.5. The use of GC preferably out of the three batches of powder Magnolol pieces optimum grinding process to produce study results show that the reference drug peaks(12) was significantly less than the peak of three batches of powder(both 20), while the number of chromatographic peaks three batches of powder, peak height and peak time highly similar, indicating that after the use of the optimum crushing, Magnolia pieces uniform quality, process is stable, you can map the gas phase characteristics Magnolol standard peak area pieces more than 0.01% of the number of peaks as a quality evaluation of a Magnolia officinalis standard pieces.All in all, the optimum preferred herein that can significantly improve the utilization of Magnolia bark pieces, and the powder mass produce the different batches very uniform, indicating that this process is very stable, and the preliminary identified two Magnolia officinalis standard pieces quality evaluation.