| Objective:To study the cardiopulmonary fitness improvement of primary hypertension who finished three months vigorous walk, to provides the basis for hypertension exercise prescription.Methods:135 primary hypertension patients, wear accelerometer to assess the level of daily activity, and collect physiological and biochemical indexes. Then we arrange subjects take part in exercise stress test, collect heart rate、blood pressure and gas metabolism data of each level of exercise. Subjects were randomly divided into experimental group (T) and control group (c), experimental group participated in an exercise intervention for three months, while the control group kept their original lifestyle. We take account of their exercise stress test results and accelerometer data, finally developed exercise prescription:it is include 12 weeks exercise, four days a week, every day exercise 50 minutes: including 10 minutes preparatory activities, intermediate 30 minutes 70% maximum heart rate target heart rate brisk walking, last 10 minutes walking recovery process. Wear polar monitor exercise heart rate, a total of 68 patients complete the final three months of brisk walking in the experimental group, control group of 27 patients. three months after the collected again physiological and biochemical indexes and exercise treadmill test.Result:1、135 subjects wearing accelerometers, the daily average intensity activity duration in the proportion of the number of 20-30 minutes to reach 22%, moderate intensity activity duration greater than or equal to 30 minutes of the proportion accounted for less than 12%. More than 20 minutes of sustained moderate intensity activities three times a week and more than three times the number of a total of 50 people.2、After exercise intervention experiment group the movement time (P<0.05), the maximum heart rate (P<0.05), met (P<0.05) and peak oxygen uptake (P< 0.05) obviously increased compared with before intervention; control group of exercise time and three months before compared with no significant changes, while the experimental group and the control group compared to the experimental group stem prognosis movement maximum heart rate (P<0.05), movement time (P<0.01) to the met value (P<0.05) and peak oxygen uptake (P<0.01) were significantly higher than those in the control group.3、the heart rate of exercise test of experimental group compared with its results before intervention decreased significantly:the quiet heart rate (P<0.05), the second stage (P<0.05), and the third stage of the load (P<0.05) and post intervention testing heart rate for the first level load was lower in the intervention before the first stage of the test center rate (P<0.01); while the control with no change in the test group of heart rate before and after the intervention at all levels of exercise. The experimental group and the control group compared to the dry prognosis during the exercise test in the experimental group, the quiet heart rate (P <0.05), first level (P<0.05), the second stage (P<0.05), the third level (P<0.05), the four level (P<0.05) test in heart rate were significantly lower than those of the control group movement of the heart rate.4、VO2max (ml/kg) was calculated by stepwise regression analysis of the correlation between the peak value of the oxygen intake of the variables and the physical activity time, gender, BMI, MET, and HRmax as the independent variables:Y=2791.043+46.02X1+176.46X2+9.951X3+191.726X4Y represents VO2max (ml/kg), X1 represents BMI, X2 represents Met, X3 represents HRmax, X4 represents gender (female is 1, male is 2), R=0.837, R2=0.7 and so on.5、After exercise intervention, the SBP of each level in the experimental group were significantly lower than those before three months, the first stage (P=0.037), second (P=0.042), third (P=0.029), and the change of DBP had no significant difference. At the same time, the control group after three months of exercise test each index found that there is no difference. After exercise, the SBP was significantly higher in the control group than in the experimental group.6、Experimental group before and after intervention and C-reactive protein (CRP), low density lipoprotein, triglyceride and blood glucose were decreased (P <0.05) compared to, weight, waist circumference, hip circumference, white cell dielectric) compared with those before intervention decreased significantly (P< 0.01);the control intervention group before and after the index had no significant change, body weight, waist to hip ratio but a slight growth, between the two groups difference is obvious. At the same time, dry prognosis of experimental groups of high sensitive C-reactive protein, leukocyte interleukin 6 were significantly lower than that in the control group (P<0.01), low density lipoprotein, hip circumference and blood sugar is also lower than the control group (P<0.05).7、Movement before and after the intervention by the participants in the movement appeared the symptom limited stop exercise test, the intervention before systolic blood pressure too high a 39% and 41%; exercise intervention after simple systolic blood pressure too high with 27 people, accounted for 28.4%; normal reaches a predetermined number of moving load from the previous 30 to 45,the proportion of by 31.58%, increased to 47.37%.8、The prediction equation of peak systolic blood pressure: Y=67.094+0.771X1-3.904X2, R=0.52, R2=0.501,Y expressed the highest systolic blood pressure, and X1 was the representative of quiet time systolic blood pressure, X2 representative of quiet CRP.9、First load exercise test in patients with hypertensive response to exercise, the experimental group do the prognosis of movement time is the first test was obviously higher (P<0.05), movement of the maximum heart rate and maximum contraction pressure and diastolic blood pressure (P<0.01) compared with the first decreased; and after SBP recovery time compared with the first decreased significantly (P<0.01). Experimental group and control group, the experimental group movement time (p<0.01), maximum diastolic blood pressure (p<0.01) and SBP (p<0.05) recovery time after exercise were significantly changed.Conclusion:1、three months of vigorous walking intervention subjects cardiopulmonary fitness increased:MET, exercise time, peak oxygen uptake increased significantly;2、After exercise intervention, exercise After exercise intervention, the SBP of each level in the experimental group were significantly lower than those before three months, in two and three months later exercise blood pressure and related risk factors of change:change of exercise blood pressure tends to be stable, the motion of the center of vascular risk occurrence rate is reduced, the related risk factors (blood glucose, blood lipid and inflammatory factor) concentration decreased significantly;3、Exercise peak systolic pressure and the relationship between C-reactive protein and blood pressure in the quiet high sensitive C most closely;4、After exercise intervention, exercise capacity increases, cardiovascular regulation has significant improvement of exercise high blood pressure group. |
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