Study On The Differences Of Objective Indicators Among TCM Syndromes In Type 2 Diabetes Mellitus

Objective: The paper in order to study the distribution of traditional Chinese medicine(TCM)syndromes based on type 2 diabetes mellitus(T2DM)and explore the link between TCM syndromes and objective indicators,through collecting TCM syndromes and objective indicators in 100 T2 DM patients and analysing them statistically,trying to provide reference basis for objectification and treatment of TCM syndromes in T2 DM.Methods: This study adopts the method of epidemiological investigation,it collected 100 patients from the Second Affiliated Hospital of Dalian Medical University in January 2016,then concluded the TCM syndromes of diabetes mellitus strictly according to “Clinical Research Guiding Principles of New Medicine in Chinese Medicine(Trial Implementation)”[1],and recorded its objective index level such as fasting glucose(GLU)and glycosylated hemoglobin(Hb A1c).Using SPSS 22.0software to dispose the data statistically after they have been inputed and inspected,then preliminarily summarized and analyzed the association between TCM syndromes and objective indicators in T2 DM.Results: 1.Distribution of TCM syndromes in T2 DM as follows : qi and yin deficiency type(35%)> both yin and yang deficiency type(18%)=blood stasis and qi stagnation type(18%)> yin deficiency heat superfluity type(17%)> phlegm huimd(hot)intrinsic type(12%);2.From the point of gender,There has no sstatistically significant difference in allthe TCM syndrome diffrentiations(P > 0.05).3.From the point of age,blood stasis and qi stagnation type and both yin and yang deficiency type are significantly higher than the other three types(P < 0.05 or 0.01),phlegm huimd(hot)intrinsic type is significantly lower than all the other four types(P< 0.05 or 0.01);4.From the course of the disease,the course according to the follow increasing trend:yin deficiency heat superfluity type < phlegm huimd(hot)intrinsic type <qi and Yin deficiency type <blood stasis and qi stagnation type < both yin and yang deficiency type,the difference have statistical significance,P < 0.05 or 0.01;5.From the body mass index(BMI),tphlegm huimd(hot)intrinsic type is significantly higher than all the other four types(P < 0.05 or 0.01);6.From the GLU,qi and Yin deficiency type is significantly higher than both yin and yang deficiency type and blood stasis and qi stagnation type(P < 0.05);7.From the Hb A1 c,qi and Yin deficiency significantly higher than blood stasis and qi stagnation type(P < 0.05);8.Look from the lipid:(1)look from the total cholesterol(TC),tphlegm huimd(hot)intrinsic type is significantly higher than yin deficiency heat superfluity type,both yin and yang deficiency type and blood stasis and qi stagnation type(P< 0.05 or 0.01);yin deficiency heat superfluity type is significantly lower than tphlegm huimd(hot)intrinsic type and qi and Yin deficiency type(P < 0.01).(2)Look from triglyceride(TG),tphlegm huimd(hot)intrinsic type is significantly higher than than all the other four types(P < 0.01).(3)Look from the high-density lipoprotein cholesterol(HDL-C),there has no sstatistically significant difference in all the TCM syndromes(P > 0.05).(4)From the point of low-density lipoprotein cholesterol(LDL-C),qi and Yin deficiency type is significantly higher than yin deficiency heat superfluity type and both yin and yang deficiency type(P < 0.05 or 0.01);9.Look from the insulin resistance(IR)and fasting C-Peptide(C-P):there has no sstatistically significant difference in all the TCM syndromes(P > 0.05).Conclusions: 1.the distribution of TCM syndromes with type 2 diabetes hascertain regularity,there are more qi Yin deficiency type patients in clinica;2.There exist differences between all the TCM syndromes in age,the course of disease,BMI,GLU,Hb A1 c,TC,TG and LDL-C,and haven’t been found differences in gender,HDL-C,IR and C-P;3.the low level of TC can be used as a reference in yin deficiency heat superfluity type;It can be used as a reference in phlegm huimd(hot)intrinsic type that the attack of age is low or there are one or more higher levels of BMI,TC and especially TG;One or more higher levels of GLU,Hb A1 c and LDL-C can be used as a reference in qi Yin deficiency type;4.The most obvious abnormity is the the level of BMI and dyslipidemia of the patients with phlegm huimd(hot)intrinsic type,which hints that curative effect maybe better when use phlegm turbidity reduction medicine for the patients of T2 DM combined hyperlipidemia based on syndrome differentiation and treatment.