Clinical Study Of “Sanqizhitong Decoction”in Treating Phlegm-stasis Blocking Collateral Type Stable Angina Pectoris

Objective:To evaluate the clinical efficacy of Sanqizhitong decoction in treating phlegm-stasis blocking collateral type stable angina pectoris and to explore its mechanism of action.Methods: The 60 patients met the inclusion criteria were randomly divided into treatment group and control group,30 cases in each.The control group was received conventional treatment of western medicine and the other plus Sanqizhitong decoction.The treatment cycle was 6 weeks.Observe and record the angina pectoris,ECG,the amount of nitroglycerin,TCM syndrome,Seattle angina questionnaire score before and after treatment.All data were analyzed with SPSS 17.0.Results:After treatment,two groups of patients with angina pectoris,ECG,the amount of nitroglycerin,Seattle table scores,TCM Comprehensive Index and the total score of TCM Syndrome were improved compared with before treatment,and the treatment group is better than the control group(P<0.01,P<0.05).The treatment group single integral was lower than those before treatment(P<0.01).The control group single integral(except insomnia and coating on the tongue)reduction was statistically significant.After treatment,the treatment group integral(except short breath and insomnia) was lower than the control group(P<0.05). During the experiment,there was no record of safety index anomaly and adverse reactions.Conclusions:Sanqizhitong decoction combined with western medicine treatment can significantly improve the clinical symptoms with phlegm-stasis blocking collateral type stable angina pectoris.The effect is better than pure western routine therapy,and the clinical application is safe and reliable.