Clinical Observation Of CO₂ Fractional Laser On Facial Corticosteroid-dependent Dermatitis With High Altitude Area

Objective: Observe the efficacy of the CO₂ Fractional laser in treatment of facial corticosteroid-dependent dermatitis in the high altitude area.Method: Eighty patients of facial corticosteroid-dependent dermatitis were randomized into simply drug group and combination group:both of the two groups were applied compound glycyrrhizin capsules and levocetirizine dispersible tablets,and oral 3 weeks;At the same time,combination group were guided CO₂ fractional laser,once every four weeks.The course of treatment was 12 weeks.The effect was measured respectively at week 4,8 and 12.Results: The effective rates of the combination group were signifcantly higher than simply drug group at 4 weeks?8 weeks and 12 weeks,and the difference was statistically signifcant?P<0.05?.The third month after the treatment,The subjective symptoms,face diffused erythema and tumid,acneform lesion,skin aging and angiotelectasis in combination group were better than that of simply drug group significantly?P<0.05?.But there were no statistical difference between two groups about polytrichia and pigmentation?P>0.05?.Conclusion: The compound glycyrrhizin capsules and levocetirizine dispersible tablets combination with the CO₂ fractional laser is an effective and low recurrence rate in treatment of facial corticosteroid-dependent dermatitis in the high altitude area.