Study On The Characteristics Of The Syndrome Elements In Chronic Atrophic Gastritis With Weakness Of Spleen And Stomach

Objective:"The spleen-stomach weakness pattern" is one of the most common syndrome types.It is found that the clinical effect is not so good when using a method of reinforcing Qi Strengthening Spleen.So the syndrome theory is used to explore the characteristics of chronic atrophic gastritis with spleen and stomach weakness.In addition to the spleen and stomach,the disease-plagued syndromes are not only qi-deficiency,but also whether they are miscellaneous disease-plagued,pathogenic elements.and study their distribution characteristics of syndromes in different pathological types,in order to further clarify the chronic atrophy of the spleen and stomach weakness.The pathogenesis of gastritis provides a theoretical reference for clinical treatment of syndrome differentiation.Methods:From February 2017 to January 2018,98 cases of CAG patients with spleen and stomach weakness were admitted to the outpatient department and inpatient department of spleen and stomach disease department of the second people’s hospital affiliated to fujian university of traditional Chinese medicine.A questionnaire survey was conducted on the information table of syndrome element,gastroscope and pathological features,and syndrome integrals were calculated using the syndrome differentiation software system.The statistical methods analyzed the syndromes of the total samples,pathological atrophy,metaplasia of intestinal metaplasia,and the distribution of syndromes of intraepithelial neoplasia,summarized and concluded.Result:1.Spleen and stomach weakness type of chronic atrophic gastritis syndrome involved in the stomach,spleen,liver,kidney,heart,large intestine,the distribution of the disease location of the syndrome level was statistically significant(P<0.05).2.The syndromes of chronic atrophic gastritis with spleen-stomach weakness were related to stomach,spleen,liver,kidney,heart,and large intestine in different pathological types.The distribution of atrophy and intestinal metaplasia were different(P<0.05).There was no difference in the distribution of neoplasia(P>0.05).The pathological progression of diseased "liver" and"kidney" syndromes was different(P<0.01),and metaplasia and intraepithelial neoplasia of "liver" were risk factors(P<0.05,OR values were 2.963 and 12.314>1);"kidney" was an important influencing factor of intestinal metaplasia(P<0.05,OR values was 0.607<1).3.Spleen and stomach weakness type of chronic atrophic gastritis syndrome distribution characteristics:deficiency syndrome elements involved in qi deficiency,yang deficiency,yin deficiency,blood deficiency.solid syndrome elements involved in qi stagnation,wetness,sputum,food product,blood stasis.There was a difference in the distribution of syndromes(P<0.05).4.Spleen and stomach debilitating chronic atrophic gastritis in different pathological types of pathogenic syndrome distribution characteristics:atrophy followed by qi stagnation,wet,qi deficiency,yang deficiency,sputum,food product,yin deficiency,blood stasis,blood deficiency,syndrome level distribution Difference(P<0.05).Intestinal metaplasia followed by qi stagnation,Qi deficiency,yang deficiency,wetness,sputum,food product,blood stasis,yin deficiency,and blood deficiency.The distribution of syndromes was different(P<0.05).The syndromes of intraepithelial neoplasia were phlegm,qi stagnation,yang deficiency,qi deficiency,wetness,blood stasis,food product,yin deficiency,and blood deficiency,but the distribution of their syndromes was not statistically significant(P>0.05).There were differences in the pathological progression of the "Yang-Deficiency" and "Deficiency"syndromes(P<0.05),and "Yang-Deficiency" was a risk factor for pathological progression(P<0.05,OR values were 2.113,3.819,7.425>1),"Deficiency" was a risk factor for intraepithelial neoplasia(P<0.05,OR values was 1.01>1).Conclusion:1.In addition to the spleen,stomach,Spleen and stomach weak chronic atrophic gastritis was associated highly with liver and kidney."liver" and "kidney" were closely related to pathological progress,so it was suggested that the clinical treatment of Spleen and stomach weak chronic atrophic gastritis was not only to adjust the spleen and stomach,’but also to improve the liver and kidney,and to achieve multiple organs and tone.2.The pathogenesis of chronic atrophic gastritis with spleen-stomach weakness is not only qi deficiency,but also coexist with pathological factors such as yang deficiency,sputum,qi stagnation,wetness,blood stasis,as well as food accumulation,and "yang deficiency" and"deficiency" were related to pathological progress,which suggesting that clinical treatment of spleen and stomach weakness chronic atrophic gastritis were needed to deal with the rationale of temperature Yang,Huayu Tongluo and so on.