The Impact Of DRD2 Gene Polymorphisms And Parenting Styles On Creative Problem Finding

Creativity is an important driving force in social development as well as an indispensable capacity in individual development. Creative problem finding ability is an important component in creativity thinking, which is under the influence of environment and individual themselves. Among the environmental factors, parenting styles are often studied by reseachers. The researchers in the study found it is not the same parenting style that has consistent results in children's creativity, revealing the role of parenting styles is affected by the children's own characteristic. With the development of the molecular genetics, the genetic foundation of human cognition and behavior not only became a hot spot of researches in psychological field, but also one of the leading edge subjects in the world. Creativity researchers also began to systematically explore the relationship between genetic polymorphism and creativity in all fields, trying to uncover the genetic basis of individual differences in creativity from the perspective of molecular genetics. But the research is still in its infancy, in these studies about the genetic basis of creativity, DRD2 genes relatively got more attention and some meaningful conclusions were obtained. In view of this, the present study examined the relationship between creative problem finding ability and DRD2 gene polymorphism, parenting style on the basis of existing research.The present study explored the influence of DRD2 gene polymorphisms and parenting style on creative problem finding. Creativity and parenting style were measured by DT test and Parenting Authority Questionnaire among 246 unrelated healthy Chinese undergraduates. Fifteen single-nucleotide polymorphisms covering DRD2 were genotyped and genomic DNA for each participant was extracted from peripheral venous blood samples. The main conclusions were summarized as follows:1. DRD2 gene rs4648317 polymorphism had significant main effect on originality performance(under the recessive model): the originality scores in thecombined C/C and C/T genotypes were higher than those in the T/T group. DRD2 gene rs1800497 polymorphism had significant main effect on flexibility performance(under the domain model): the flexibility scores in the combined T/T and T/C genotype were higher than those in the C/C group.2. We found two blocks in haplotype analysis in the haplotype block ?,consisting of rs4648319, rs4436578, rs7122246, rs2283265, rs1076560, rs6277,rs6276, rs6279, rs6278 and rs1800497 SNPS. In which the CTGGCCGCGC haplotype significantly predict fluency and flexibility scores, while the CTGTACAGTT haplotype significantly predict flexibility scores.3. There were significantly interaction between DRD2 gene and parenting styles on creative problem finding indicating that:(1) rs4245148 polymorphism significantly interacted with paternal authoritarian in predicting fluency performance. Specifically, paternal authoritarian could negatively predict fluency performance in the carriers of the T allele of rs4245148.(2) There were two significantly two-way interactions(rs1076560 × maternal permissive, rs1076560×paternal authoritarian) in predicting originality performance.Specifically, maternal permissive could positively predict originality performance in the A/A and C/A group and paternal authoritarian could negatively predict originality performance in the A/A and C/A group.(3) rs4648319 polymorphism significantly interacted with paternal authoritarian in predicting originality performance. Specifically, paternal authoritarian could negatively predict originality performance in the C/C group.(4) There were two significantly two-way interactions( rs6279 × paternal authoritative, rs4436578×paternal authoritarian)in predicting flexibility performance.Specifically, paternal authoritative could negatively predict flexibility performance in the C/C group of rs6279 and paternal authoritarian could negatively predict flexibility performance in the C/C and C/T groups of rs4436578.