| Pressure ulcer mainly occurs in long-term bed can't independent activities and critical condition of the patients,is one of the most common clinical complications,seriously reduces patients' survival and quality of life,increases the cost of treatment,patients' economic burden heavier.Even sepsis and septicemia can result in systemic failure and death.Severe cases of sepsis and septicemia can result in systemic failure and death.The study shows that the incidence of pressure ulcer is on the rising trend in recent years.2016 guide will pressure sores renamed pressure damage,points out that it is in the skin and(or)potential limitations of subcutaneous soft tissue injury,usually occurs in the bone juga or skin contact with medical equipment.This stress lesion can be characterized by localized tissue damage but complete or open ulcers due to severe and/or prolonged stress combined with shear force.The pretreatment of pressure ulcer is mainly prevention.The treatment of pressure ulcer is mainly divided into conservative treatment and surgical treatment.Pressure ulcers in traditional Chinese medicine calls " bedsores ",think that the main responsibility is to the"blood deficiency" and "blood stasis",and "burst infected," on the treatment mainly by promoting blood circulation to remove blood stasis,promoting pus discharge and tissue regeneration.In recent years,the research on the external use of traditional Chinese medicine to treat pressure ulcers has emerged,and the dialectical treatment of traditional Chinese medicine has been widely recognized in the treatment of pressure ulcers,and has achieved good curative effect.This study the choice of drugs in addition to follow the traditional Chinese medicine in the treatment of pressure ulcers promoting blood circulation to remove blood stasis,poison,the principle of the production of more related theory,combined with modern pharmacology selection in vitro bactericidal antibacterial anti-inflammatory effects under the environment of Chinese gall,cattail pollen,honeysuckle,with generation of plasma and promote wound healing effect is combined with white and is intended to provide a new method for clinical treatment of pressure ulcers.Objective:To compare the efficacy of homemade pressure sore pharmaceutical preparation wet-compressing therapy and Western medicine iodophor in the treatment of stage ? to ?pressure sores,and explore the possible mechanism of action so as to facilitate further clinical promotion.Methods:this study was a prospective randomized controlled study.64 patients with pressure ulcers were randomly divided into two groups.During the experiment,including 1 case of loss by clinical death.2 cases of ? period was unable to complete wound healing therapy in patients with pressure ulcers and fall off;2 cases were lost due to loss of visit;2 cases were removed due to other serious d.iseases.There were 57 cases of complete treatment,29 of them,13 males andl6 females,with an average age of 72.45 plus or minus 7.48 years.In the control group,there were 28 cases,14 males and 14 females,with an average age of 71.32 + 8.07 years old,and the two groups were 0.694>0.05.It's comparable.The risk factors of the two groups were evaluated,and the average score of Braden's score test group was 17.24 plus or minus 2.90,while the control group was 17.21 + + 2.50.P=0.157>0.05,and the differen-ces between the two groups were not statistically significant and comparable.In the control group,the routine iodide was given,and the treatment group was given the homemade pre-ssure sore pharmaceutical preparation.Using the Braden scale and PUSH scale for five time node(into groups,7,14,21,28 days),the experimental group and control group in thegeneral conditions and practices in pressure ulcer wound observation records.SPSS20.0 software was usecd for data analysis.Results:general comparison:pressure sores through Braden assessment on day 7,14 days,21 days,28 days basic conditions of the experimental group and the control group one by one analysis,P values were greater than 0.05,there is no clear difference,treatment of two groups in the general condition(i.e.,a pressure ulcer risk assessment)affect the difference.PUSH score:the remission rate of pressure ulcers area in the experimental group and the control group was respectively 7 days:13.19%and 17.86%,respectively,and the difference between the two groups was not statistically significant(P=0.674).Day 14:62.07%and 32.14%,the difference betw-een the two groups was statistically significant(P=0.024);Day 21:86.21%and 64.29%,the difference between the two groups was statistically significant(P=0.16);Day 28:93.10%and 64.29%,the difference between the two groups was statistically significant(P=0.01).The remission rate of the wound fluid volume in the experimental group and the control group were as follows;7 days:10.34%and 7.14%,respectively;the differen-ces between the two groups was not statistically significant(P=0.669);Day 14:62.07%and 25%,the difference between the two groups was statistically significant(P=0.05).Day 21:86.21%and 39.29%;the difference between the two groups was statistically significant(P=0.0);Day 28:100%and 60.17%,the difference between the two groups was statistically significant(P=0.001).In the experimental group and control group,the remission rate of pre-ssure ulcer tissue type was 7 days:37.93%and 14.29%,respectively,and the difference be-tween the two groups was statistically significant(P=0.043).Day 14:86.21%and 57.14%,respectively.The difference between the two groups was statistically significant(P=0.043);Day 21:96.55%and 82.14%,the difference between the two groups was statistically significant(P=0.02);Day 2.8:100%and 89.26%,with statistically significant differencebetween the two groups(P=0.018).Wound to restore the total curative effect evaluation:28 days after treatment,the general characteristics of the two groups of wound recovery is:the experimental group of remission rate was 100%,the control response rate was 75%,through chi-square test,P = 0.006,thedifference was statistically significant,the treatment of 28 days,the sample treatment efrfect in the test group is better than the control group.Conclusion:homemade pressure sore pharmaceutical preparation paste wet apply pressure sores ??? period curative effect is superior to the traditional iodine volts switching,and can quickly reduce drainage amount,improve wound tissue types,reduce the area of pressure ulcers,relieve patients' pain. |
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