| Purpose and significance of researchTraditional Chinese medicine is the gem of Chinese tradition medicine and traditional culture,it promotes the development of traditional medicine in our country,and it is an indispensable part of TCM theory system.The dosage of Chinese herbal pieces is an important factor affecting the effectiveness and safety of traditional Chinese medicine.Is the basic part of the Theory of Chinese medicine,is the basis of all the drug efficacy,since ancient times there is "the Secret of Chinese Medicine in quantity,Chinese medicine in the amount of treatment in the quantity," said the Qing doctors Wang Qingzhing that "the medicine is important,the weight more important",It can be seen that the selection of prescription dosage determines the clinical curative effect of traditional Chinese medicine to some extent.To fully explain the importance of Chinese medicine dosage in TCM due to the treatment of people,the current dose standard is based on the dosage in the Pharmacopoeia,and the dosage in Pharmacopoeia does not play a guiding role in clinical rational use of drugs,May even become the shackles of the development of Chinese medicine application.Therefore,it is of great significance to make a set of reasonable dosage standard for Chinese herbal medicine.In this study,one of the commonly used Chinese herbal medicines Pinellia ternate was selected as the research object,taking the dose as the starting point,and the clinical efficacy and safety as the core and the belonging point,in order to find out the use rule of Chinese herbal medicine and the rational application of modern clinical Chinese herbal medicine.To provide the basis for the revision of the use of the new Pharmacopoeia.Research methods1 Source of informationThe literature mainly includes the ancient literature and the modern literature,this research will use the knowledge net,the Whipple,Wan fang and so on the modern literature which retrieves in the whole research the modern academic support,all over the whole research all aspects,has not listed separately,but has carried on the comparatively systematic research to the ancient literature separately.Sources of ancient documents Selected the representative of the history of the medical classics nine,including the Western Han Dynasty "Huan Di nei Jing",the Eastern Han Dynasty "Shang Han Lun","Jin Kui Yao Lue",the Tang Dynasty "Bei Ji Qian Jin Yao Fang "Qian Jin Yi Fang ",the Song Dynasty"Tai Ping Hui Min He Ji Ju Fang" "Tai Ping Sheng Hui Fang",the Ming Dynasty "Jing Yue Quan Shu",the Qing Dynasty " Yi Zong Jin Jian".The formulae containing Pinellia ternate were studied.Source of modern literatureModern literature by CNKI,VIP and Wan Fang database retrieved Hospital prescription data sourceWith the help of hospital information platform,the prescription of Pinellia ternate was screened out by randomly sampling 2017.4-2018.3 Chinese Medicine prescriptions of a three-grade TCM hospital.The prescription information of Pinellia ternate includes patient ID,patient's age,sex of patient,prescription number,clinical diagnosis,name of Chinese herbal medicine,medicine number,drug payment,amount,weight,single weight,time of opening medicine,division,prescription doctor,entrust.2 Statistical analysis methodIn this paper,Microsoft Office Excel and SPSS software are used to input and analyze data.The statistical contents include the interval of dose distribution,the average dosage,the most commonly used dose,the range of common dose and so on,and then the analysis of the dose and efficacy of the use of Pinellia temata is completed.Research results1 Study on the dosage of Pinellia ternate under different dosage forms The dosage range of middle Pinellia ternata is 0.2-1652g,the most commonly used dose is 20.6g,the average dosage is 105.94g,the most commonly used dose is 20.6-41.3g;the use range of Pinellia temata is 0.2-82.6g,the most commonly used dose is 20.6g,the average dosage is 25.89g;the use dose range of the pill is 0.2-2478g,the most commonly used dose is 41.3g and the average dosage is 200.74g;the paste is 200.74g;the average dosage is 200.74g;the average dosage is 200.74g;the average dosage is 200.74g;the average dosage is 200.74g;the average dosage is 200.74g;The dosage of Pinellia ternata was 3.6-63g,the most commonly used dose was 37.3g,and the average dosage was 43.9g;the dosage of Pinellia ternata was 13.9-27.8g,the most used dose was 13.9g,and the average dosage was 93.22g.2 Relationship between dosage and efficacy of Pinellia ternate in decoction and its compatibility lawIn view of the most common use of Decoction in the modern clinical dosage forms in the ancient times,the decoction was used as the main research object,and the relationship between the dosage and efficacy of Pinellia ternata in the decoction and the regularity of compatibility were further studied.The most effective of the decoction is "eliminating swelling and dissipating the knot".The efficacy of the first three is the efficacy of the Pinellia ternata recorded in the Pharmacopoeia,that is "dampness and dampness and phlegm,antieusal nausea and swelling and dissipating knot".The dose range of each effect is relatively large,but the average dose is basically between 40-60g and the most commonly used dose is 20.6g.Pinellia ternata dose is the most comprehensive in the range of 40-60g and 80-100g.Pinellia ternate has the most compatibility with licorice,ginseng and cinnamon.3 The research results of the dosage of Pinellia ternate in hospital prescription.Women were more than men taking the Pinellia ternata,50-59 years old using the most Pinellia ternata,the average age of Pinellia was 50.6 years old,the most common use of Pinellia was 30-69 years old,the most common Banxia department was the digestive department,the second was Department of respiration,third were blood and oncology department,which fully reflected the effect of Banxia "elimination of the ruffian knot,dampness and dampness and phlegm,anti nausea".In addition,the use of the decoction of Pinellia ternata and the dosage of several kinds of processed products in the beverage were studied.It was found that the dosage of the decoction was twice as high as that of the traditional decoction,and the use rate of the Pinellia ternata was the highest in the Pinellia ternata.It was combined with the efficacy of several kinds of artillery products.The most of the utility.The dose range of Pinellia ternata was 1.5-30g,the most commonly used dose was 10g and the average dosage was 10.3G;the use dose range of the normal Pinellia ternata was 3-24g,the most commonly used dose was 10g,the average dose was 9.9g;the use dose range of Jiang Banxia was 3-20g,the most commonly used dose was 10g,the average dose was 9.7g.The dose range of Pinellia Pinelliae is 2-24g,the most commonly used dose is 10g,the average dosage is 10.2g,the range of the dosage is 3-30g,the most commonly used dose is 10g,the average dosage is 10.5G;the dose range of the ginger is 4-15g,the most commonly used dose is 10g,the average dosage is used.For 9.9g,the dose range of the raw Pinellia ternata was 10-15g,the most commonly used dose was 10g,15g,the average dosage was 12.5g;the dose range of Banxia koji was 5-12g,the most used dose was 10g,and the average dosage was 8.5g.And the most compatible drugs are Poria,tangerine peel,bupleurum and scutellaria.Research conclusions and significanceIn conclusion,can be found in both ancient and today,all have a large number of pinellia use use dose of the prescription dose is higher than pharmacopoeia,show the dosage range in pharmacopoeia already cannot satisfy the need of modern clinical treatment of diseases,it has restricted the development of pinellia tuber.Compared in this study the ancient pinellia dosage,the ancient one of pinellia most commonly used dose range of 20.6 to 20.6 g,the average dose between 40 to 60 g,basically in the 40-60 g and 80-100-g range has the efficacy of the most comprehensive,the hospital prescription of pinellia tuber is the most commonly used dosage of 10 g,average dosage is about 10 g,it can be seen that the viewpoints and pinellia commonly used in modern prescription dose the most complete range and effect of the dosage range were higher pharmacopoeia prescribed dose range,so according to the research result suggested that the new pharmacopoeia standards,expanding the use of this decoction dose range. |
PDF Full Text Request